Immunoglobulin G4-Related Aortic Disease
| Autor: | Yoshio Misawa, Satoshi Uesugi, Shin-ichi Ohki, Akira Sugaya |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Aortography Computed Tomography Angiography Biopsy IgG4-related aortopathy Plasma Cells Aorta Thoracic Autoimmunity 030204 cardiovascular system & hematology Aortic disease Immunoglobulin G Autoimmune Diseases 03 medical and health sciences Aortic aneurysm Blood Vessel Prosthesis Implantation 0302 clinical medicine immunoglobulin G4 Internal medicine Immunoglobulin g4 medicine Humans Letter to the Editor Aortic dissection medicine.diagnostic_test biology Aortic Aneurysm Thoracic Aortitis business.industry Gastroenterology General Medicine Middle Aged medicine.disease Immunohistochemistry Aortic Dissection Treatment Outcome 030228 respiratory system Acute Disease Cardiology biology.protein Surgery Cardiology and Cardiovascular Medicine business aortic aneurysm |
| Zdroj: | Annals of Thoracic and Cardiovascular Surgery |
| ISSN: | 2186-1005 1341-1098 |
| Popis: | Immunoglobulin G subclass 4-related disease (IgG4-RD) is a recently recognized systemic inflammatory disease characterized by an elevated serum IgG4 level and an IgG4-positive lymphocyte infiltrate mainly in exocrine tissues. Previous reports documented IgG4-RD in several cardiovascular disorders. We present a case of type A aortic dissection associated with IgG4-RD. A 52-year-old man diagnosed with a type A aortic dissection was referred for surgical treatment. He underwent emergency hemiarch reconstruction with a prosthetic graft. His postoperative recovery was uncomplicated. Histopathologic examination of his aortic tissue showed marked adventitial thickening with fibrosis and an IgG4-positive plasma cell infiltrate. He was diagnosed with type A aortic dissection incidentally complicated by IgG4-RD. The relationship between IgG4-RD and the pathogenesis of aortic dissection remains unknown and requires further investigation. |
| Databáze: | OpenAIRE |
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