Early versus Conventional Treatment for Patent Ductus Arteriosus in Preterm Infants
| Autor: | Ermengol Coma Redon, Queralt Ferrer Menduiña, Ángeles Linde Sillo, Dimpna C. Albert, Félix Castillo Salinas, Júlia Candel-Pau |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Time Factors Birth weight Indomethacin Population Gestational Age Risk Assessment Drug Administration Schedule Cohort Studies Treatment and control groups Ductus arteriosus medicine Humans education Ductus Arteriosus Patent Retrospective Studies education.field_of_study Chi-Square Distribution Dose-Response Relationship Drug Descriptive statistics business.industry Infant Newborn Conventional treatment Obstetrics and Gynecology Gestational age Cardiovascular Agents Retrospective cohort study Echocardiography Doppler Survival Rate Treatment Outcome medicine.anatomical_structure Pediatrics Perinatology and Child Health Female business Infant Premature Follow-Up Studies |
| Zdroj: | American Journal of Perinatology. 30:289-296 |
| ISSN: | 1098-8785 0735-1631 |
| DOI: | 10.1055/s-0032-1324696 |
| Popis: | Objective After the introduction of a new protocol based on the early treatment with indomethacin for patent ductus arteriosus, the objective of this study was to assess the safety and efficacy of this new practice in comparison with the safety and efficacy of the conventional treatment in a high-risk population. Study Design We conducted a retrospective cohort study including 154 newborns with an average gestational age of 26.4 weeks (1.37 standard deviation) and an average birth weight of 855 g (201.5 standard deviation). A statistically descriptive analysis was performed with SPSS Statistics Pack version 17.0. Results and Conclusions We did not find any statistically significant differences in the clinical features of the two treatment groups, nor in the main efficacy, morbidity, and mortality results. |
| Databáze: | OpenAIRE |
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