Health-related quality of life predicts length of hospital stay and survival rates for pediatric patients receiving allogeneic hematopoietic cell transplantation

Autor: Shih-Hsiang Chen, Ying-Mei Liu, Lin Lin, Tang-Her Jaing, Chia-Ling Wu, Yu-Chuan Wen, Pei-Yin Weng
Rok vydání: 2021
Předmět:
Zdroj: Quality of Life Research. 30:3421-3430
ISSN: 1573-2649
0962-9343
DOI: 10.1007/s11136-021-02887-1
Popis: We examined the association between health-related quality of life (HRQoL) of pediatric patients during hospitalization for allogeneic hematopoietic cell transplantation (HCT) and length of hospital stay, and 1-year survival. Primary family caregivers were proxy-assessors for the Pediatric Quality of Life (PedsQL) Stem Cell Transplant Module at three time points: 5-days pre-HCT (T0); 14-days post-HCT (engraftment, T1); and 1-week before hospital discharge (T2). Cox regression analyses determined predictors of the overall 1-year survival after allogeneic HCT. Thirty-nine eligible caregivers completed all assessments. The mean age of the pediatric patients was 9.07 years (SD = 5.2). PedsQL Stem Cell Transplant Module scores decreased from 71.33 (SD = 13.26) at T0 to 55.41(SD = 13.05) at T1 (p
Databáze: OpenAIRE