Comparison of ordinal versus Agatston coronary calcification scoring for cardiovascular disease mortality in community-living individuals
Autor: | C. Michael Wright, Katherine J. Blair, Joachim H. Ix, Christina L. Wassel, Matthew A. Allison, Michael H. Criqui, Dena E. Rifkin, Cindy Morgan |
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Rok vydání: | 2014 |
Předmět: |
Male
medicine.medical_specialty Time Factors endocrine system diseases Whole body imaging Coronary Artery Disease Coronary Angiography Risk Assessment Severity of Illness Index Article Coronary artery disease Predictive Value of Tests Risk Factors Internal medicine Epidemiology Severity of illness medicine Humans Whole Body Imaging Radiology Nuclear Medicine and imaging cardiovascular diseases Vascular Calcification Cardiac imaging Aged Aged 80 and over business.industry Case-control study nutritional and metabolic diseases Middle Aged Prognosis medicine.disease Coronary Vessels Case-Control Studies Predictive value of tests cardiovascular system Cardiology Female Radiology Tomography X-Ray Computed Cardiology and Cardiovascular Medicine business Agatston score |
Zdroj: | The International Journal of Cardiovascular Imaging. 30:813-818 |
ISSN: | 1573-0743 1569-5794 |
DOI: | 10.1007/s10554-014-0392-1 |
Popis: | Coronary artery calcification (CAC) by the Agatston method predicts cardiovascular disease (CVD), but requires cardiac gated computed tomography (CT) scans, a procedure not covered by most insurance providers. An ordinal CAC score (scored 0-12 based on artery number and extent of calcification involvement) can be measured on standard chest CTs. However, the correlation of ordinal and Agatston CAC scores and their relative association with CVD mortality is uncertain, which we sought to determine. Nested case-control study. Community-living individuals undergoing "whole body" CT scans for preventive medicine. 4,544 consecutive patients with CT scans, were followed from 2000 to 2009. We selected cases who died of CVD (n = 57) and age, sex, and CT slice-thickness matched each case to three controls (N = 171). Cardiac gated 3 mm chest CTs and non-gated 6 mm standard chest CTs. CVD death over 9 years follow-up. The intra- and inter-reader kappa for the ordinal CAC score was 0.90 and 0.76 respectively. The correlation of Agatston and ordinal CAC scores was 0.72 (p |
Databáze: | OpenAIRE |
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