Comparison of intra-articular injection of plasma rich in growth factors versus hyaluronic acid following arthroscopy in the treatment of temporomandibular dysfunction: A randomised prospective study
| Autor: | Andrés Blanco-Carrión, Bogdan Stavaru Marinescu, Jorge Arenaz-Bua, Annahys López-Betancourt, Jacinto Fernández-Sanromán, Alberto Costas-López, Martín Fernández-Ferro |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Visual analogue scale Osteoarthritis Injections Intra-Articular 03 medical and health sciences chemistry.chemical_compound Arthroscopy Plasma Young Adult 0302 clinical medicine Intra articular Hyaluronic acid Medicine Humans Prospective Studies Hyaluronic Acid Prospective cohort study Aged medicine.diagnostic_test business.industry Significant difference 030206 dentistry Middle Aged Temporomandibular Joint Disorders medicine.disease Combined Modality Therapy Surgery Temporomandibular joint medicine.anatomical_structure Otorhinolaryngology chemistry 030220 oncology & carcinogenesis Intercellular Signaling Peptides and Proteins Female Oral Surgery business |
| Zdroj: | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 45(4) |
| ISSN: | 1878-4119 |
| Popis: | Purpose The main objective of our study was to evaluate the effectiveness of the injection of plasma rich in platelet-derived growth factors (PRGF) versus hyaluronic acid (HA) following arthroscopic surgery in patients diagnosed with internal derangement of the temporomandibular joint (TMJ) with osteoarthritis (OA). Materials and methods A total of 100 patients were randomised into two study groups. Group A (n = 50) received an injection of PRGF, and Group B (n = 50) received an injection of HA. The mean age was 35.5 years (range 18–77 years), and 88% of the patients were women. The pain intensity (visual analogue scale) and the extent of maximum mouth opening before and after the procedure were statistically analysed. Results Better results were observed in the group treated with PRGF, with a significant reduction in pain at 18 months, compared with HA treatment. Regarding mouth opening, an increase was observed in both groups, with no significant difference. Conclusions The injection of PRGF following arthroscopy is more effective than the injection of HA with respect to pain in patients with advanced internal derangement of the TMJ. |
| Databáze: | OpenAIRE |
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