Advanced glycation end products, galectin-3, matrix metalloproteinase-9 activity in men with heart failure and concomitant benign prostatic hyperplasia with androgen deficiency

Autor: Nedzvetsky V.S., Sirenko O.Yu., Tkachenko V.A., Kuryata O.V.
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Medicni perspektivi; Vol. 26 No. 4 (2021); 67-73
Медичні перспективи; Том 26 № 4 (2021); 67-73
Medičnì Perspektivi, Vol 26, Iss 4, Pp 67-73 (2021)
ISSN: 2307-0404
2786-4804
Popis: The aim was to evaluate serum levels of matrix metalloproteinases-9 activity, advanced glycation end products, galectin-3, C-reactive protein in men with heart failure and benign prostatic hyperplasiawith testosterone deficiency. The testosterone level was determined by immune-enzyme analysis. The content of advanced glycation end products in plasma were analysed by quantitative autofluorescence. The metalloproteinases-9 activity was estimated with fluorometry. The level of galectin-3, C-reactive protein was determined by immune-enzyme analysis. 1stgroup was made up by the men with heart failure and benign prostatic hyperplasia with testosterone deficiency; 2ndgroup – by the men without testosterone deficiency. The men with heart failure and benign prostatic hyperplasia with testosterone deficiency had a significantly higher level of advanced glycation end products, galectin-3, matrix metalloproteinases-9 activity in comparison with men with heart failure without testosterone deficiency (p
Databáze: OpenAIRE