| Autor: |
Fabritz, L., Connolly, D.L., Czarnecki, E., Dudek, Dariusz, Guasch, E., Haase, D., Huebner, T., Zlahoda-Huzior, A., Jolly, K., Kirchhof, P., Obergassel, J., Schotten, U., Vettorazzi, E., Winkelmann, S.J., Zapf, A., Schnabel, R.B. |
| Přispěvatelé: |
Fysiologie, RS: Carim - H08 Experimental atrial fibrillation |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
European Heart Journal-Digital Health, 3(4), 610-625. Oxford University Press |
| ISSN: |
2634-3916 |
| DOI: |
10.1093/ehjdh/ztac067 |
| Popis: |
AimsSimplified detection of atrial arrhythmias via consumer-electronics would enable earlier therapy in at-risk populations. Whether this is feasible and effective in older populations is not known.Methods and resultsThe fully remote, investigator-initiated Smartphone and wearable detected atrial arrhythmia in Older Adults Case finding study (Smart in OAC—AFNET 9) digitally enrolled participants ≥65 years without known atrial fibrillation, not receiving oral anticoagulation in Germany, Poland, and Spain for 8 weeks. Participants were invited by media communications and direct contacts. Study procedures adhered to European data protection. Consenting participants received a wristband with a photoplethysmography sensor to be coupled to their smartphone. The primary outcome was the detection of atrial arrhythmias lasting 6 min or longer in the first 4 weeks of monitoring. Eight hundred and eighty-two older persons (age 71 ± 5 years, range 65–90, 500 (57%) women, 414 (47%) hypertension, and 97 (11%) diabetes) recorded signals. Most participants (72%) responded to adverts or word of mouth, leaflets (11%) or general practitioners (9%). Participation was completely remote in 469/882 persons (53%). During the first 4 weeks, participants transmitted PPG signals for 533/696 h (77% of the maximum possible time). Atrial arrhythmias were detected in 44 participants (5%) within 28 days, and in 53 (6%) within 8 weeks. Detection was highest in the first monitoring week [incidence rates: 1st week: 3.4% (95% confidence interval 2.4–4.9); 2nd–4th week: 0.55% (0.33–0.93)].ConclusionRemote, digitally supported consumer-electronics-based screening is feasible in older European adults and identifies atrial arrhythmias in 5% of participants within 4 weeks of monitoring (NCT04579159). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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