Iron(II)-Catalyzed Trifluoromethylation of Potassium Vinyltrifluoroborates

Autor:	Todd D. Senecal, Stephen L. Buchwald, Andrew T. Parsons
Přispěvatelé:	Massachusetts Institute of Technology. Department of Chemistry, Parsons, Andrew T., Senecal, Todd D., Buchwald, Stephen Leffler
Rok vydání:	2012
Předmět:	Trifluoromethylation Potassium chemistry.chemical_element Stereoisomerism Homogeneous catalysis General Medicine Fluorine General Chemistry Article Catalysis Transmetalation chemistry Organometallic Compounds Organic chemistry Ferrous Compounds Iron catalyst Copper
Zdroj:	PMC
ISSN:	1433-7851
Popis:	Exchanging BF[subscript 3] by CF[subscript 3]: The title reaction proceeds under exceedingly mild reaction conditions and provides 2-arylvinyl- and 2-heteroarylvinyl-substituted substrates with E/Z selectivities of more than 95:5. Experimental observations suggest that the reaction does not proceed through a transmetalation of the RBF[subscript 3]K species to the iron catalyst. National Institutes of Health (U.S.) (Grant GM46059) National Institutes of Health (U.S.) (Postdoctoral Fellowship F32M093532) National Science Foundation (U.S.) (Grant CHE-9808061) National Science Foundation (U.S.) (Grant DBI-9729592) National Institutes of Health (U.S.) (Grant 1S10RR13886-01)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559f2e8b35d7756e80c86d02d2c365b2 https://doi.org/10.1002/anie.201108267 Zobrazit plný text záznamu Plný text