Increased IL-18 Levels in Seminal Plasma of Infertile Men with Genital Tract Infections
| Autor: | Argiris Kourtis, Yvoni Fragouli, Gabor Huszar, Hakan Cakmak, Aydin Arici, Ioannis Matalliotakis |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Immunology Varicocele Orchitis Semen Biology Infections Gastroenterology Andrology Interferon-gamma Klinefelter Syndrome Internal medicine Cryptorchidism medicine Humans Immunology and Allergy Mumps Infertility Male Genitourinary system Interleukin-18 Obstetrics and Gynecology Interleukin Middle Aged medicine.disease Sperm Cytokine Reproductive Medicine Interleukin 18 Genital Diseases Male Klinefelter syndrome |
| Zdroj: | American Journal of Reproductive Immunology. 55:428-433 |
| ISSN: | 1600-0897 8755-8920 |
| DOI: | 10.1111/j.1600-0897.2006.00380.x |
| Popis: | Problem Interleukin (IL)-18 is a novel cytokine, previously known as interferon (IFN)-γ inducing factor. We evaluated the levels of IL-18 and IFN-γ in seminal plasma (SP) of fertile and infertile men. Method of study Semen samples were obtained by masturbation from 80 men, and were examined for the levels of IL-18 and IFN-γ by enzyme-linked immunosorbent assay. Seven groups were included: (i) fertile men (n = 18), (i) infertile men with genital tract infections (n = 17), (iii) with varicocele (n = 15), (iv) with Klinefelter syndrome (n = 6), (v) with cryptorchidism (n = 7), (vi) with mumps orchitis (n = 7), and (vii) with idiopathic testicular lesions (n = 10). Results Mean levels of IL-18 were higher in SP from infertile men with genital tract infections compared with SP from other groups except Klinefelter syndrome (P |
| Databáze: | OpenAIRE |
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