A comparison study of dual-energy spectral CT and 18F-FDG PET/CT in primary tumors and lymph nodes of lung cancer
| Autor: | Gülnihan Eren, Nurgül Orhan Metin, Osman Kupik, Medeni Arpa, Yavuz Metin |
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| Přispěvatelé: | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kupik, Osman, Eren, Gülnihan, Metin, Nurgül Orhan, Arpa, Medeni |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Lung Neoplasms
030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography medicine Humans Radiology Nuclear Medicine and imaging Lung cancer Retrospective Studies Large-cell neuroendocrine cancer medicine.diagnostic_test business.industry Modality-Based (US CT MRI PET-CT) Imaging: Original Article medicine.disease Primary tumor Positron emission tomography Positron-Emission Tomography Comparison study Adenocarcinoma Fdg pet ct Lymph Lymph Nodes Radiopharmaceuticals Cardiology and Cardiovascular Medicine Nuclear medicine business Tomography X-Ray Computed |
| Zdroj: | Diagn Interv Radiol |
| Popis: | PURPOSE: We aimed to investigate whether there is a correlation between dual-energy spectral computed tomography (DESCT) and (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) parameters in primary tumor and metastatic lymph nodes in patients with newly diagnosed lung cancer. METHODS: Primary tumor and metastatic lymph nodes of 68 patients diagnosed with lung cancer were evaluated retrospectively with (18)F-FDG PET/CT and DESCT imaging. The histologic subtypes were adenocarcinoma (n=29), squamous cell carcinoma (SCC) (n=26), small cell lung cancer (SCLC) (n=11), and large cell neuroendocrine cancer (LCNEC) (n=2). In terms of PET parameters, SUVmax, SUVmean, SULmax, SULmean, SULpeak, and normalized SUL values were obtained for primary tumors and metastatic lymph nodes. In terms of DESCT parameters, maximum and mean iodine content (IC), normalized IC values, iodine enhancement (IE) and normalized IE values were calculated. RESULTS: We found no correlation between DESCT and (18)F-FDG PET/CT parameters in primary tumors and metastatic lymph nodes. In addition, no correlation was found in the analysis performed in any of the histologic subgroups. In patients with a primary tumor |
| Databáze: | OpenAIRE |
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