Chill coma in the locust,Locusta migratoria, is initiated by spreading depolarization in the central nervous system
| Autor: | Phinyaphat Srithiphaphirom, Kristin E. Spong, R. Meldrum Robertson |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Central Nervous System
030110 physiology 0301 basic medicine Central nervous system Intracellular Space lcsh:Medicine Locusta migratoria Article 03 medical and health sciences 0302 clinical medicine medicine Coordinated movement Animals Coma lcsh:Science 030304 developmental biology Neurons 0303 health sciences Multidisciplinary biology lcsh:R fungi food and beverages Depolarization Anatomy biology.organism_classification Axons Electrophysiological Phenomena Cold Temperature Phenotype medicine.anatomical_structure Neural function lcsh:Q medicine.symptom Neuroscience 030217 neurology & neurosurgery Locust |
| Zdroj: | Scientific Reports Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017) |
| DOI: | 10.1101/162198 |
| Popis: | The ability of chill-sensitive insects to function at low temperatures limits their geographic ranges. They have species-specific temperatures below which movements become uncoordinated prior to entering a reversible state of neuromuscular paralysis. In spite of decades of research, which in recent years has focused on muscle function, the role of neural mechanisms in determining chill coma is unknown. Spreading depolarization (SD) is a phenomenon that causes a shutdown of neural function in the integrating centres of the central nervous system. We investigated the role of SD in the process of entering chill coma in the locust, Locusta migratoria. We used thermolimit respirometry and electromyography in whole animals and extracellular and intracellular recording techniques in semi-intact preparations to characterize neural events during chilling. We show that chill-induced SD in the central nervous system is the mechanism underlying the critical thermal minimum for coordinated movement in locusts. This finding will be important for understanding how insects adapt and acclimate to changing environmental temperatures. |
| Databáze: | OpenAIRE |
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