Simultaneously Transplanted Pancreas Improves Salivation and Reduces Oral Fungal Infections Incidence in Type 1 Diabetic Renal Transplant Recipients
| Autor: | Andrzej Wiecek, Aleksander Owczarek, Damian Niedzielski, Rafał Wiench, Mikołaj Musiał, Iwona Niedzielska, Piotr Choręza, Dariusz Skaba, Jacek Ziaja, Aureliusz Kolonko, Robert Król, Agnieszka Machorowska-Pieniążek |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Saliva medicine.medical_treatment Salivary Gland Diseases Pancreas transplantation Oral hygiene Gastroenterology Diabetes Complications Transplanted pancreas Internal medicine Diabetes mellitus Humans Medicine Kidney transplantation Transplantation Kidney business.industry Incidence Incidence (epidemiology) Middle Aged medicine.disease Kidney Transplantation Diabetes Mellitus Type 1 medicine.anatomical_structure Mycoses Kidney Failure Chronic Female Surgery Pancreas Transplantation Mouth Diseases Salivation business |
| Zdroj: | National Information Processing Institute |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2020.01.105 |
| Popis: | Background Long-lasting diabetes mellitus may lead to numerous pathologies in the oral cavity. The aim of the study was to assess the condition of the oral cavity, caries intensity, salivary parameters, and incidence of oral fungal infections in patients with type 1 diabetes (T1D) and end-stage renal disease (ESRD) after kidney transplantation (KTx) or simultaneous kidney and pancreas transplantation (SPK). Methods Twenty-one patients after SPK, 18 T1D patients after KTx, and 14 kidney recipients without diabetes (control group) were included in the study. Donor sources complied with Helsinki Congress and the Declaration of Istanbul. Results Approximal plague index in SPK (80% [68%-90%]) was comparable to KTx (80% [37.5%-92.5%]) but higher than in control group (46% [35%-50%]). All 3 groups did not differ in terms of decayed-missing-filled tooth index: 22.3 ± 4.8 vs 22.5 ± 4.5 vs 19.1 ± 4.9, respectively. Normal saliva resting secretion and consistency were more common in SPK (71.4% and 52%, respectively) than in KTx (27.8% and 50.0%, respectively). Stimulated saliva volume in the SPK, KTx and controls, pH value, and buffering capacity were comparable. In KTx higher incidence of Candida albicans infection (55.6%) compared with SPK (23.8%) and controls (no infection) was observed. Conclusions Simultaneously transplanted pancreas improves salivation and reduces the incidence of oral fungal infections in T1D kidney recipients. The severity of caries is higher and oral hygiene is worse in T1D kidney recipients compared with patients after KTx without diabetes. |
| Databáze: | OpenAIRE |
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