Phaco-UCP; combined phacoemulsification and ultrasound ciliary plasty versus phacoemulsification alone for management of coexisting cataract and open angle glaucoma: a randomized clinical trial
| Autor: | Eman A. Awad, Ameera G Abdelhameed, Magda A Torky, Yousef A Alzafiri |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Intraocular pressure
medicine.medical_specialty Visual acuity Open angle glaucoma genetic structures medicine.medical_treatment Glaucoma Cataract law.invention Tonometry Ocular 03 medical and health sciences 0302 clinical medicine Randomized controlled trial lcsh:Ophthalmology law Ophthalmology Glaucoma surgery medicine Humans 030212 general & internal medicine Intraocular Pressure Phacoemulsification business.industry OAG General Medicine Cataract surgery medicine.disease eye diseases Phaco-UCP Treatment Outcome lcsh:RE1-994 030221 ophthalmology & optometry sense organs Ultrasound ciliary plasty medicine.symptom business Glaucoma Open-Angle Research Article |
| Zdroj: | BMC Ophthalmology, Vol 21, Iss 1, Pp 1-10 (2021) BMC Ophthalmology |
| ISSN: | 1471-2415 |
| Popis: | Background Various surgical techniques have been described, to be combined with cataract surgery in glaucoma patients, aiming for an additional reduction of intraocular pressure (IOP), hence minimizing the burden of anti-glaucoma medication (AGM). Ultrasound ciliary plasty (UCP) is a recent microinvasive glaucoma surgery (MIGS) recommended for primary and refractory glaucoma. This study was conducted to evaluate the safety and efficacy of a new technique; combined phacoemulsification and ultrasound ciliary plasty (Phaco-UCP) as a primary surgical treatment for coexisting cataract and open angle glaucoma. Methods A randomized clinical trial, including 61 eyes of 61 patients with visually significant cataract and open angle glaucoma, randomized to either Phaco-UCP (study group; 31 eyes) or phacoemulsification alone (Phaco-alone) (control group; 30 eyes). Primary outcomes included reduction in IOP and/or the number of AGM. Secondary outcomes included visual acuity improvement and complications. Qualified Success was defined as an IOP reduction ≥ 20% from baseline value, with an IOP 6–21 mmHg, with no additional AGM or glaucoma surgery. Failure was defined as either Results At 18 months postoperatively, Phaco-UCP group had a median IOP reduction of 7 mmHg (Q1, Q3 = 3, 10) compared to 2 mmHg (Q1, Q3 = 2, 3) in Phaco-alone group (P PP =0.3)] at baseline to [1 (Q1,Q3 = 1, 2), 2 (Q1,Q3 = 2, 2)] respectively, (P Conclusion Phaco-UCP is a simple, safe and effective procedure for management of coexisting cataract and open angle glaucoma. Trial registration ClinicalTrials.gov identifier, NCT04430647; retrospectively registered. June 12, 2020. |
| Databáze: | OpenAIRE |
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