Visceral adiposity index as a predictor of clinical severity and therapeutic outcome of PCOS
| Autor: | Sai-Hua Zheng, Xue-Lian Li |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Disease Type 2 diabetes Intra-Abdominal Fat Severity of Illness Index Anovulation 03 medical and health sciences 0302 clinical medicine Endocrinology Insulin resistance Non-alcoholic Fatty Liver Disease Internal medicine medicine Hyperinsulinemia Humans Menstruation Disturbances Inflammation 030219 obstetrics & reproductive medicine business.industry Hyperandrogenism Obstetrics and Gynecology medicine.disease Polycystic ovary Cardiovascular Diseases Female Metabolic syndrome Insulin Resistance business Polycystic Ovary Syndrome |
| Zdroj: | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 32(3) |
| ISSN: | 1473-0766 |
| Popis: | Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disease which often accompany with abnormal fat distribution. Visceral adiposity has association with abnormal lipid metabolic, pro-inflammatory activity, insulin resistance (IR) and hyperandrogenism. Increased visceral adiposity raises the risk of metabolic syndrome, type 2 diabetes and cardiovascular (CV) events, and aggravates ovulatory dysfunction and hyperandrogenism in PCOS women. Visceral adiposity index (VAI), a simple surrogate maker of visceral adipose dysfunction and visceral adiposity, is a predictor of IR, and link hyperinsulinemia, hyperandrogenism and anovulation. This review aims to discuss the visceral adiposity situation in PCOS women, and suggests that VAI may be a useful predictor of clinical severity and therapeutic outcome of PCOS. |
| Databáze: | OpenAIRE |
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