Luteinising hormone releasing hormone for incomplete descent of the testis
Autor: | A M Klidjian, J M Johnstone, P G Swift |
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Rok vydání: | 1985 |
Předmět: |
Male
Clinical Trials as Topic medicine.medical_specialty Luteinising hormone releasing hormone business.industry Placebo Inguinal canal law.invention Gonadotropin-Releasing Hormone Double blind medicine.anatomical_structure Endocrinology Double-Blind Method Randomized controlled trial law Internal medicine Cryptorchidism Pediatrics Perinatology and Child Health medicine Humans Child business Administration Intranasal Research Article |
Zdroj: | Archives of Disease in Childhood. 60:568-571 |
ISSN: | 1468-2044 0003-9888 |
DOI: | 10.1136/adc.60.6.568 |
Popis: | Forty boys with 54 incompletely descended testes took part in a double blind, controlled trial of intranasal luteinising hormone releasing hormone. In the control (placebo) group of 18 boys there was no significant change in testicular descent and all required orchidopexy; in the 22 treated boys, however, 12 of 29 testes (42%) were found in a lower position. This study supports the idea that a trial of intranasal luteinising hormone releasing hormone (1200 micrograms/day for 28 days) will help clarify the need for orchidopexy in at least 30% of boys with incomplete descent of the testis, particularly those in whom the testes have emerged from the inguinal canal. |
Databáze: | OpenAIRE |
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