Assessment of individual-based perfluoroalkly substances exposure by multiple human exposure sources
| Autor: | Jong-Hyeon Lee, Jeong-Eun Oh, Da-Hye Kim |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Environmental Engineering Adolescent Health Toxicology and Mutagenesis 0211 other engineering and technologies Food Contamination 02 engineering and technology 010501 environmental sciences complex mixtures 01 natural sciences Eating Young Adult Individual based Republic of Korea Humans Environmental Chemistry Ingestion Medicine Child Waste Management and Disposal Aged 0105 earth and related environmental sciences Aged 80 and over Fluorocarbons 021110 strategic defence & security studies business.industry Drinking Water digestive oral and skin physiology Dust Environmental Exposure Middle Aged Pollution Alkanesulfonic Acids Human exposure Child Preschool Environmental chemistry Environmental Pollutants Female Caprylates business |
| Zdroj: | Journal of Hazardous Materials. 365:26-33 |
| ISSN: | 0304-3894 |
| Popis: | Individual exposure of perfluoroalkyl substances (PFASs) was assessed by analyzing serum, food, dust, drinking water, and hand wipes from 50 individuals. The PFASs concentrations in serum were correlated most strongly with exposure to PFASs through the (direct and indirect) ingestion of dust (p 0.01). Daily PFOA intakes were estimated to be 2.07 ng/kg/day from food, 0.003 ng/kg/day from dust, 0.053 ng/kg/day from hand-to-mouth activity, and 0.020 ng/kg/day from drinking water. Daily perfluorooctanesulfonic acid (PFOS) intakes were estimated to be 0.689 ng/kg/day from food, 0.001 ng/kg/day from dust, 0.018 ng/kg/day from hand-to-mouth activity, and 0.005 ng/kg/day from drinking water. The daily PFOA and PFOS intakes calculated for individuals in this study and in group/scenario based exposure assessment of previous studies were compared. The estimated PFOS intake on individual basis (0.695 ng/kg/day) was a little bit higher than the intake on group/scenario basis (0.652 ng/kg/day). However, the estimated daily PFOA intake on individual basis (1.41 ng/kg/day) was about four times higher than the intake on group/scenario basis (0.339 ng/kg/day). Among the exposure pathways, food ingestion was major contributor to the total daily PFOA and PFOS intakes on individuals (99% of total intake) and group/scenario basis (64% of total intake). |
| Databáze: | OpenAIRE |
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