Chemobrain: A Pilot Study Exploring the Severity and Onset of Chemotherapy-Related Cognitive Impairment
| Autor: | DaiWai M. Olson, Sonja E. Stutzman, C. Kelly Moore, Laurin L. Priddy |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Trail Making Test Antineoplastic Agents Pilot Projects General Practitioner Assessment of Cognition Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Humans Medicine In patient Prospective Studies Cognitive impairment Aged General Environmental Science Chemotherapy 030504 nursing business.industry Symptom management Significant difference Middle Aged 030220 oncology & carcinogenesis Physical therapy General Earth and Planetary Sciences Female Observational study Cognition Disorders 0305 other medical science business |
| Zdroj: | Clinical Journal of Oncology Nursing. 23:411-416 |
| ISSN: | 1538-067X 1092-1095 |
| Popis: | BACKGROUND Chemotherapy-related cognitive impairment refers to a cluster of symptoms commonly referred to as "chemobrain". To date, nursing literature on the progression of and tools used to evaluate chemobrain is limited. OBJECTIVES The purpose of this pilot study was to explore the onset of chemobrain in patients who recently began chemotherapy treatment, as well as those who have been receiving chemotherapy for an extended period of time. METHODS This prospective, nonrandomized, observational pilot feasibility study used the General Practitioner Assessment of Cognition and the Trail Making Test Parts A and B to examine chemotherapy-related cognitive impairment symptoms in patients undergoing chemotherapy treatment. FINDINGS Paired t tests showed a significant difference in scores on the Trail Making Test Part A from baseline to eight months (p < 0.05) and in scores on the Trail Making Test Part B from four to eight months (p < 0.05). The mixed results suggest that the Trail Making Test Parts A and B may not be effective for testing chemotherapy-related cognitive impairment in patients. |
| Databáze: | OpenAIRE |
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