Elevated serum periostin is associated with liver stiffness and clinical outcome in biliary atresia

Autor:	Wanvisa Udomsinprasert, Paisarn Vejchapipat, Nopaorn Phavichitr, Sittisak Honsawek, Yong Poovorawan, Voranush Chongsrisawat
Rok vydání:	2015
Předmět:	Male musculoskeletal diseases Pathology medicine.medical_specialty animal structures Health Toxicology and Mutagenesis Clinical Biochemistry Jaundice Enzyme-Linked Immunosorbent Assay macromolecular substances Periostin Biochemistry Gastroenterology Elevated serum Liver Function Tests Biliary Atresia Biliary atresia Liver stiffness Internal medicine medicine Humans Postoperative Period Prospective Studies Child business.industry equipment and supplies medicine.disease Liver Elasticity Imaging Techniques Female medicine.symptom business Cell Adhesion Molecules Biomarkers
Zdroj:	Biomarkers. 20:157-161
ISSN:	1366-5804 1354-750X
DOI:	10.3109/1354750x.2015.1045032
Popis:	Objective: To analyze serum periostin and liver stiffness in postoperative biliary atresia (BA).Methods: A total of 60 BA patients and 14 controls were enrolled. Serum periostin levels were analyzed by ELISA. Liver stiffness measurement was determined by transient elastography.Results: Biliary atresia patients had significantly higher periostin and liver stiffness values than controls. Serum periostin levels were remarkably increased in BA patients with jaundice compared to those without jaundice. Moreover, serum periostin was correlated with liver stiffness.Conclusions: Serum periostin was associated with liver stiffness in BA. Thus, serum periostin has potential as a parameter reflecting the severity in BA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557dac0d1aced4bcd9f2f848a23d4ad3 https://doi.org/10.3109/1354750x.2015.1045032 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.