Airway and esophageal stenting in patients with advanced esophageal cancer and pulmonary involvement
| Autor: | Denis L. Rousseau, Arnaud Bourdin, Laurent Verdier, Mathieu Besnard, C. Arvin-Berod, Jean Baptiste Noel, F. Paganin, Laurent Cuissard, Laurent Schouler, Jean-Philippe Becquart |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Lung Diseases
Male medicine.medical_specialty Esophageal Neoplasms medicine.medical_treatment lcsh:Medicine Bronchi Esophagus Esophageal stent Medicine Humans cardiovascular diseases Radiology and Medical Imaging/Computer Tomography lcsh:Science Respiratory Medicine Aged Neoplasm Staging Retrospective Studies Multidisciplinary medicine.diagnostic_test business.industry lcsh:R Stent Retrospective cohort study Bronchial Diseases Middle Aged equipment and supplies Endoscopy Surgery Gastroenterology and Hepatology/Endoscopy Radiation therapy Trachea medicine.anatomical_structure surgical procedures operative Female Stents lcsh:Q Gastroenterology and Hepatology/Esophagus business Airway Complication Research Article |
| Zdroj: | PLoS ONE, Vol 3, Iss 8, p e3101 (2008) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Background Most inoperable patients with esophageal-advanced cancer (EGC) have a poor prognosis. Esophageal stenting, as part of a palliative therapy management has dramatically improved the quality of live of EGC patients. Airway stenting is generally proposed in case of esophageal stent complication, with a high failure rate. The study was conducted to assess the efficacy and safety of scheduled and non-scheduled airway stenting in case of indicated esophageal stenting for EGC. Methods and Findings The study is an observational study conducted in pulmonary and gastroenterology endoscopy units. Consecutive patients with EGC were referred to endoscopy units. We analyzed the outcome of airway stenting in patients with esophageal stent indication admitted in emergency or with a scheduled intervention. Forty-four patients (58±\−8 years of age) with esophageal stenting indication were investigated. Seven patients (group 1) were admitted in emergency due to esophageal stent complication in the airway (4 fistulas, 3 cases with malignant infiltration and compression). Airway stenting failed for 5 patients. Thirty-seven remaining patients had a scheduled stenting procedure (group 2): stent was inserted for 13 patients with tracheal or bronchial malignant infiltration, 12 patients with fistulas, and 12 patients with airway extrinsic compression (preventive indication). Stenting the airway was well tolerated. Life-threatening complications were related to group 1. Overall mean survival was 26+/−10 weeks and was significantly shorter in group 1 (6+/−7.6 weeks) than in group 2 (28+/−11 weeks), p |
| Databáze: | OpenAIRE |
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