The change of corrin-amides to carboxylates leads to altered structures of the B12-responding btuBriboswitch

Autor:	Stefan Mundwiler, Roland K. O. Sigel, Sofia Gallo, Roger Alberto
Rok vydání:	2011
Předmět:	Vitamin b Riboswitch Stereochemistry Static Electricity Carboxylic Acids Molecular Conformation Ring (chemistry) Catalysis chemistry.chemical_compound Static electricity Escherichia coli Materials Chemistry Side chain RNA metabolism Molecular Structure Chemistry Hydrogen bond Escherichia coli Proteins Corrin Metals and Alloys Membrane Transport Proteins Hydrogen Bonding General Chemistry Amides Surfaces Coatings and Films Electronic Optical and Magnetic Materials Vitamin B 12 Ceramics and Composites Corrinoids RNA Bacterial Outer Membrane Proteins
Zdroj:	Chem. Commun.. 47:403-405
ISSN:	1364-548X 1359-7345
Popis:	By applying four different acid derivatives of vitamin B(12), we demonstrate that the H-bonding pattern and the electrostatic environment provided by each side chain of the corrin ring are crucial for the correct structural rearrangement of the btuB riboswitch of E. coli.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557ba61b9c1cd7259051cc26261847f8 https://doi.org/10.1039/c0cc02447c Zobrazit plný text záznamu