The influence of dopamine on spatial vision
| Autor: | J.P. Harris, O.T. Phillipson, J.E. Calvert, J A Leendertz |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Vision Disparity Visual acuity genetic structures Dopamine media_common.quotation_subject Retina Contrast Sensitivity Vision disorder Ophthalmology medicine Humans Contrast (vision) Psychiatry media_common Chemistry Dopamine antagonist medicine.anatomical_structure Sensory Thresholds Schizophrenia Female Spatial frequency medicine.symptom Pupillometry medicine.drug |
| Zdroj: | Eye. 4:806-812 |
| ISSN: | 1476-5454 0950-222X |
| DOI: | 10.1038/eye.1990.127 |
| Popis: | Contrast thresholds for, and contrast matches between, stationary gratings of three spatial frequencies (0.5, 2, and 8 c/deg) were measured on eight subjects with a history of schizophrenia, just before, and again two to three days after, a therapeutic injection of depot neuroleptic. The drug enhanced sensitivity at the low, and reduced it at the medium and high spatial frequency. After injection, subjects required more contrast to match the apparent contrast of the high, and less contrast to match that of the low, to that of the medium spatial frequency. Pupillary measurements suggested that these effects were not due to drug-induced changes in pupil size. The results are discussed in terms of the functional role of dopamine in the retina, and a possible application in therapy for amblyopia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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