Drug utilization in the Maastricht Study
| Autor: | Nielen, Johannes T H, Driessen, Johanna H M, Dagnelie, Pieter C, Boonen, Annelies, van den Bemt, Bart, van Onzenoort, Hein A W, Neef, Cees, Henry, Ronald M A, Burden, Andrea M, Sep, Simone J S, van der Kallen, Carla J, Schram, Miranda T, Schaper, Nicolaas, Stehouwer, Coen D A, Smits, Luc, de Vries, Frank, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology |
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| Přispěvatelé: | Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Clinical Pharmacy, RS: Carim - V01 Vascular complications of diabetes and metabolic syndrome, RS: NUTRIM - R3 - Respiratory & Age-related Health, Interne Geneeskunde, Epidemiologie, MUMC+: MA Reumatologie (9), RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, MUMC+: HVC Pieken Maastricht Studie (9), RS: Carim - V02 Hypertension and target organ damage, MUMC+: MA Endocrinologie (9), MUMC+: MA Interne Geneeskunde (3), MUMC+: MA Med Staf Artsass Interne Geneeskunde (9), MUMC+: MA Maag Darm Lever (9), MUMC+: MA Hematologie (9), MUMC+: MA Medische Oncologie (9), MUMC+: MA Nefrologie (9), RS: CAPHRI - R5 - Optimising Patient Care, Farmacologie en Toxicologie, MUMC+: DA KFT Medische Staf (9) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Drug Utilization
Male medicine.medical_specialty Diabetes Mellitus Type 2/drug therapy Population Health/statistics & numerical data participation bias Population PARTICIPATION Maastricht Study Netherlands/epidemiology Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] 03 medical and health sciences 0302 clinical medicine Hypnotics and Sedatives/therapeutic use Epidemiology medicine Anti-Anxiety Agents/therapeutic use Diabetes Mellitus Humans 030212 general & internal medicine Prospective Studies education Prospective cohort study Aged RISK education.field_of_study Participation bias business.industry Drug Utilization/statistics & numerical data Respiratory System Agents/therapeutic use DIABETES-MELLITUS General Medicine Middle Aged 3. Good health Type 2/drug therapy 030220 oncology & carcinogenesis Population study Observational study Female epidemiology type 2 diabetes business drug utilization Cohort study Demography |
| Zdroj: | Medicine, 99(1). Lippincott Williams and Wilkins Medicine (Baltimore), 99, 1, pp. e18524 Medicine, 99(1):18524. LIPPINCOTT WILLIAMS & WILKINS Medicine (Baltimore), 99, e18524 |
| ISSN: | 0025-7974 |
| DOI: | 10.1097/md.0000000000018524 |
| Popis: | Contains fulltext : 218096.pdf (Publisher’s version ) (Open Access) Within the southern region of the Netherlands, the Maastricht Study is an on-going observational prospective population-based cohort study that focuses on the etiology of Type 2 diabetes mellitus (T2DM). Representativeness of the participating population is a crucial but often an unknown factor in population-based cohort studies such as the Maastricht Study. We therefore aimed to assess the representativeness of the study population by comparing drug utilization of the participants of the Maastricht Study with the general population of the Netherlands.Since T2DM patients were oversampled in this study, a sampling method was applied in order to ensure a similar distribution of T2DM over the study population. Drug use in the study population was compared with drug use in the population of the Netherlands, using a Z-test to compare 2 independent proportions.In general, drug use in the study was similar compared with national data. However, in the age group 65 to 74 years total drug use was lower in the study population (833/1000 persons) versus nationwide data (882/1000 persons). The use of pulmonary medications was lower (104/1000 persons vs 141/1000 persons) and the use of hypnotics/anxiolytics was higher (90/1000 persons vs 36/1000 persons) in the Maastricht Study as compared with national data.Drug use in the Maastricht Study population is largely comparable to that in the total Dutch population aged 45 to 74. Therefore, data on drug use by participants in the Maastricht Study can be used to perform studies assessing outcomes associated with drug use. |
| Databáze: | OpenAIRE |
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