Diffusion-weighted imaging of the entire spinal cord
| Autor: | Spyridon Kollias, Bertram J. Wilm, Anke Henning, Peter Boesiger, U Gamper, Klaas P. Pruessmann |
|---|---|
| Přispěvatelé: | University of Zurich, Boesiger, P |
| Rok vydání: | 2008 |
| Předmět: |
1607 Spectroscopy
610 Medicine & health Sensitivity and Specificity 170 Ethics White matter Lumbar Nuclear magnetic resonance 10043 Clinic for Neuroradiology Fractional anisotropy Image Interpretation Computer-Assisted medicine 2741 Radiology Nuclear Medicine and Imaging Humans 10237 Institute of Biomedical Engineering Radiology Nuclear Medicine and imaging Image resolution Spectroscopy Chemistry Phantoms Imaging Reproducibility of Results Spinal cord Image Enhancement Lumbar Spinal Cord medicine.anatomical_structure Diffusion Magnetic Resonance Imaging Spinal Cord Radiology Nuclear Medicine and imaging 1313 Molecular Medicine Molecular Medicine Algorithms Diffusion MRI Volume (compression) |
| Zdroj: | NMR in Biomedicine |
| ISSN: | 0952-3480 |
| Popis: | In spite of their diagnostic potential, the poor quality of available diffusion-weighted spinal cord images often restricts clinical application to cervical regions, and improved spatial resolution is highly desirable. To address these needs, a novel technique based on the combination of two recently presented reduced field-of-view approaches is proposed, enabling high-resolution acquisition over the entire spinal cord. Field-of-view reduction is achieved by the application of non-coplanar excitation and refocusing pulses combined with outer volume suppression for removal of unwanted transition zones. The non-coplanar excitation is performed such that a gap-less volume is acquired in a dedicated interleaved slice order within two repetition times. The resulting inner volume selectivity was evaluated in vitro. In vivo diffusion tensor imaging data on the cervical, thoracic and lumbar spinal cord were acquired in transverse orientation in each of four healthy subjects. An in-plane resolution of 0.7 x 0.7 mm(2) was achieved without notable aliasing, motion or susceptibility artifacts. The measured mean +/- SD fractional anisotropy was 0.69 +/- 0.11 in the thoracic spinal cord and 0.75 +/- 0.07 and 0.63 +/- 0.08 in cervical and lumbar white matter, respectively. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text