Volatile Organic Compounds Contribute to Airway Hyperresponsiveness
| Autor: | Choon-Sik Park, Inseon-S Choi, An-Soo Jang, Youngil Koh |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Airway hyperresponsiveness Air Pollutants Occupational Bronchial hyperreactivity Last Concentration Atopy Risk Factors Forced Expiratory Volume Occupational Exposure Surveys and Questionnaires medicine Humans Volatile organic compounds Organic Chemicals Lung function Skin Tests Korea business.industry Smoking Case-control study General Medicine medicine.disease respiratory tract diseases Occupational Diseases Case-Control Studies Chemical Industry Anesthesia Immunology Original Article Female Methacholine Smoking status Multiple Chemical Sensitivity business Multiple chemical sensitivity medicine.drug |
| Zdroj: | The Korean Journal of Internal Medicine |
| ISSN: | 1226-3303 |
| DOI: | 10.3904/kjim.2007.22.1.8 |
| Popis: | Background : Volatile organic compounds (VOCs) in concentrations found in both the work and home environments may influence lung function. We investigated the prevalence of airway responsiveness in workers exposed to VOCs. Methods : We used allergic skin tests, nonspecific airway hyperresponsiveness testing and questionnaires to study twenty exposed workers and twenty-seven control subjects. Atopy was defined as a reactor who showed >3+ response to one or more allergens on the skin prick tests. Airway hyperresponsiveness (BRindex) was defined as log (% fall of FEV 1/ log (last concentration of methacholine) +10). Results : The VOC exposed workers, in comparison with the control subjects, tended to have a higher BRindex (1.19±0.07 vs. 1.15±0.08, respectively). Workers exposed to VOCs with atopy or smoker, as compared with the workers exposed to VOCs with non-atopy and who were non-smokers and the control subjects with non-atopy and who were non-smokers, had a significantly higher BRindex (1.20±0.05 vs. 1.14±0.06 vs. 1.10±0.03, respectively p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|