| Autor: |
E. Fea, Chiara Cremolini, Alfredo Falcone, Federica Marmorino, Patrizia Racca, S. Di Donato, G. Tonini, Luigi Boni, Francesca Bergamo, Sara Lonardi, Gianluca Masi, A. Zaniboni, Emanuela Dell'Aquila, Gianluca Tomasello, Daniela Tomcikova, Angela Buonadonna, Federica Urbano, Silvana Chiara, Monica Ronzoni, Daniele Santini, Tea Zeppola, Marta Schirripa, Giacomo Allegrini, Marco Stellato |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Annals of oncology : official journal of the European Society for Medical Oncology. 29(4) |
| ISSN: |
1569-8041 |
| Popis: |
Background Neutrophil/lymphocyte ratio (NLR), defined as absolute neutrophils count divided by absolute lymphocytes count, has been reported as poor prognostic factor in several neoplastic diseases but only a few data are available about unresectable metastatic colorectal cancer (mCRC) patients (pts). The aim of our study was to evaluate the prognostic and predictive role of NLR in the TRIBE trial. Patients and methods Pts enrolled in TRIBE trial were included. TRIBE is a multicentre phase III trial randomizing unresectable and previously untreated mCRC pts to receive FOLFOXIRI or FOLFIRI plus bevacizumab. A cut-off value of 3 was adopted to discriminate pts with low (NLR |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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