An autonomous, highly portable NMR spectrometer based on a low-cost System-on-Chip (SoC)
| Autor: | Cheng Chen, Mason Greer, David Ariando, Soumyajit Mandal |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Nuclear and High Energy Physics
Frequency response Spectrometer Computer science Preamplifier business.industry Biophysics Pulse duration 010402 general chemistry Condensed Matter Physics 01 natural sciences Biochemistry 030218 nuclear medicine & medical imaging 0104 chemical sciences Computer Science::Hardware Architecture 03 medical and health sciences 0302 clinical medicine Gate array Magnet System on a chip Field-programmable gate array business Computer hardware |
| Zdroj: | Journal of Magnetic Resonance. 299:74-92 |
| ISSN: | 1090-7807 |
| DOI: | 10.1016/j.jmr.2018.12.007 |
| Popis: | This paper describes the development of a portable and self-optimizing NMR spectrometer based on a miniaturized custom analog front-end and a System-on-Chip (SoC)-based digital back-end. The SoC integrates a field-programmable gate array (FPGA) fabric with a hard processor running a Linux operating system, thus enabling fully-autonomous operation without the need for an external computer. In the proposed approach, data captured by the FPGA fabric during regular operation is transported to the hard processor using an integrated on-chip bus for further processing. The processed results are then used to automatically estimate parameter values that optimize a suitable cost function, such as signal-to-noise ratio (SNR) per unit time. Finally, the optimized values of both electrical and NMR-related tuning parameters (e.g., preamplifier gain and frequency response, pulse length and amplitude, operating frequency, etc.) are programmed back into the front-end and back-end hardware. Experimental NMR results from various samples in a ∼0.1 T permanent magnet are presented to verify the operation of the proposed spectrometer. These demonstrate on-board Laplace inversion and automated frequency tuning to compensate for temperature changes. Preliminary 14 N NQR results are also presented. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect