Enabling Fast Pseudo-2D NMR Spectral Acquisition for Broadband Homonuclear Decoupling: The EXACT NMR Approach
| Autor: | Vadim Zorin, Alexandra Shchukina, Carlos Cobas, Craig P. Butts, Ikenna E. Ndukwe, Krzysztof Kazimierczuk |
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| Rok vydání: | 2017 |
| Předmět: |
010405 organic chemistry
Chemistry Homonuclear decoupling Nonuniform sampling Decoupling (cosmology) 010402 general chemistry 01 natural sciences Atomic and Molecular Physics and Optics Homonuclear molecule Spectral line 0104 chemical sciences Computational physics Acceleration Nuclear magnetic resonance Pure shift Sampling (signal processing) EXACT Pseudo-2D NMR spectroscopy Sensitivity (control systems) Physical and Theoretical Chemistry Non-uniform sampling Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | Ndukwe, I E, Shchukina, A, Zorin, V, Cobas, C, Kazimierczuk, K & Butts, C P 2017, ' Enabling Fast Pseudo-2D NMR Spectral Acquisition for Broadband Homonuclear Decoupling : The EXACT NMR Approach ', ChemPhysChem, vol. 18, no. 15, pp. 2081–2087 . https://doi.org/10.1002/cphc.201700474 |
| ISSN: | 1439-7641 |
| DOI: | 10.1002/cphc.201700474 |
| Popis: | Pseudo-2D NMR spectroscopy provides a means of acquiring broadband homonuclear decoupled spectra useful for structural characterization of complex molecules. However, data points concatenated in the direct dimension in these experiments are acquired over incremented time periods-leading to long acquisition times with no sensitivity benefits due to the absence of signal averaging between scans. Herein, the concept of EXACT NMR spectroscopy ("burst" non-uniform sampling of data points) is explored in pseudo-2D experiments with results revealing little or no loss in spectral quality or signal intensity despite the acceleration of acquisition-up to 400 % in some cases. |
| Databáze: | OpenAIRE |
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