Activity of esterases in plasma from Ghanaian and British subjects
| Autor: | Faith M. Williams, E. Nicholson, N. W. Woolhouse, Michael D. Rawlins, K. K. Adjepon-Yamoah |
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| Rok vydání: | 1986 |
| Předmět: |
Male
medicine.medical_specialty Aspirin esterase Black People Ghana Esterase White People Pharmacokinetics Internal medicine parasitic diseases medicine Cholinesterases Humans Pharmacology (medical) Cholinesterase Pharmacology Aspirin Plasma samples biology Aryldialkylphosphatase business.industry Paraoxonase General Medicine Phosphoric Monoester Hydrolases United Kingdom Phenylacetate Endocrinology Biochemistry biology.protein business Carboxylic Ester Hydrolases medicine.drug |
| Zdroj: | European Journal of Clinical Pharmacology. 31:485-489 |
| ISSN: | 1432-1041 0031-6970 |
| DOI: | 10.1007/bf00613529 |
| Popis: | We have measured aspirin esterase, cholinesterase, paraoxonase, and phenylacetate esterase activities in samples of plasma from British and Ghanaian subjects. Aspirin esterase, paraoxonase, and phenylacetate esterase activities were significantly lower in Ghanaians compared with British subjects. However, cholinesterase activities were similar in Ghanaian and British plasma samples. The lower esterase activities in Ghanaian plasma samples may result in higher circulating concentrations and greater pharmacological effects of drugs such as aspirin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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