Intrafibrillar Mineral May be Absent in Dentinogenesis Imperfecta Type II (DI-II)
| Autor: | John H. Kinney, Sally J. Marshall, C.H. Driessen, John A. Pople, T.M. Breunig, Grayson W. Marshall |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
0301 basic medicine Materials science Adolescent Dentinogenesis imperfecta Nucleation Mineralogy Apatite 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Nuclear magnetic resonance stomatognathic system Dentinogenesis Imperfecta Dentin medicine Humans Scattering Radiation experimenteel en klinisch onderzoek en behandeling. [Erfelijke en verworven vitreo-retinale aandoeningen] General Dentistry Small-angle X-ray scattering 030206 dentistry medicine.disease stomatognathic diseases 030104 developmental biology medicine.anatomical_structure visual_art X-ray crystallography visual_art.visual_art_medium Pulp (tooth) experimental and clinical research and treatment. [Hereditary and acquired vitreo-retinal disorders] Female Molar Third Collagen Crystallite Crystallization Tomography X-Ray Computed Synchrotrons |
| Zdroj: | Journal of Dental Research, 80, 1555-9 Journal of Dental Research, 80, 6, pp. 1555-9 |
| ISSN: | 1544-0591 0022-0345 |
| Popis: | Item does not contain fulltext High-resolution synchrotron radiation computed tomography (SRCT) and small-angle x-ray scattering (SAXS) were performed on normal and dentinogenesis imperfecta type II (DI-II) teeth. The SRCT showed that the mineral concentration was 33% lower on average in the DI-II dentin with respect to normal dentin. The SAXS spectra from normal dentin exhibited low-angle diffraction peaks at harmonics of 67.6 nm, consistent with nucleation and growth of the apatite phase within gaps in the collagen fibrils (intrafibrillar mineralization). In contrast, the low-angle peaks were almost non-existent in the DI-II dentin. Crystallite thickness was independent of location in both DI-II and normal dentin, although the crystallites were significantly thicker in DI-II dentin (6.8 nm [SD = 0.5] vs. 5.1 nm [SD = 0.6]). The shape factor of the crystallites, as determined by SAXS, showed a continuous progression in normal dentin from roughly one-dimensional (needle-like) near the pulp to two-dimensional (plate-like) near the dentin-enamel junction. The crystallites in DI-II dentin, on the other hand, remained needle-like throughout. The above observations are consistent with an absence of intrafibrillar mineral in DI-II dentin. |
| Databáze: | OpenAIRE |
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