Rhodococcus equi infection in non-HIV-infected patients. Two case reports and review
| Autor: | Claudio Farina, Silvia Ferruzzi, Filippo Mamprin, Francesca Vailati |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Diagnostic methods biology Epidemiology medicine.drug_class business.industry Antibiotics review General Medicine Clinical literature biology.organism_classification medicine.disease Surgery Therapeutic approach Pneumonia Infectious Diseases Rhodococcus equi Pleurisy Internal medicine medicine business |
| Zdroj: | Clinical Microbiology and Infection. 3:12-18 |
| ISSN: | 1198-743X |
| DOI: | 10.1111/j.1469-0691.1997.tb00245.x |
| Popis: | Objective: To review two recent cases in HIV-negative subjects in the light of literature reports (52 patients without HIV infection till 1994). Methods: Epidemiology (animal contacts, risk factors, year, country), clinical presentation, diagnostic methods (X-ray, tomography, microbiological techniques), therapeutic approach (antibiotics, surgery) and outcome were evaluated on the basis of clinical literature reports. Results: Tumors constituted an important predisposing factor and less frequently hepatobiliary pathology, rheumatologic diseases, iatrogenic causes, psychiatric pathology and trauma. Exposure to animals was reported by 55% of the patients. Pneumonia and pleurisy, without preferential localization, were detected in 50% of the patients. Etiologic diagnosis was usually obtained after an invasive collection. Combined medical therapy and surgery were required by 27.8% of the patients, and 16.7% of the patients died. Conclusions: In recent years the number of Rhodococcus equi cases has been rising also in HIV-negative patients. The infection is ubiquitous. Accurate diagnosis and the prompt selection of the most appropriate therapy depend on close cooperation between clinicians and microbiologists. |
| Databáze: | OpenAIRE |
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