Effects of calorie restriction with n-3 long-chain polyunsaturated fatty acids on metabolic syndrome severity in obese subjects: A randomize-controlled trial
| Autor: | Yen-Kuang Lin, Wing P. Chan, Hsiu Yueh Su, Brian E T G Huang, Shih Yi Huang, Wen Yi Cheng, Hsiu Chuan Lee, Yi Hao Hsu, Chien-Tien Su |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Waist Meal replacement Calorie restriction Medicine (miscellaneous) law.invention Randomized controlled trial law Internal medicine Medicine TX341-641 chemistry.chemical_classification Nutrition and Dietetics Nutrition. Foods and food supply business.industry n-3 long-chain polyunsaturated fatty acids Fish oil medicine.disease Metabolic syndrome Endocrinology Blood pressure chemistry n-6/n-3 ratio business Food Science Polyunsaturated fatty acid |
| Zdroj: | Journal of Functional Foods, Vol 19, Iss, Pp 929-940 (2015) |
| ISSN: | 1756-4646 |
| DOI: | 10.1016/j.jff.2015.01.040 |
| Popis: | Metabolic syndrome (MetS) increases the risk of type 2 DM and cardiovascular disease. We here evaluated the effects of a calorie-restriction diet with 2.13 g/day n-3 long-chain polyunsaturated fatty acid supplementation in MetS patients. The 188 participants were randomly assigned one of four calorie-restriction diets for 12 weeks: calorie-restriction (n = 44), calorie-restriction meal replacement (n = 45), calorie-restriction with fish oil (n = 44), or calorie-restriction meal replacement with fish oil (n = 44); 179 participants completed the trial. After treatment, all groups had significant reduction in waist circumference, blood pressure, and cardiometabolic parameters. Results indicate that long-chain polyunsaturated fatty acid (LC-PUFA) supplementation under calorie-restriction exert beneficial effects on metabolic parameters. |
| Databáze: | OpenAIRE |
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