Prevalence and Risk of Mild Cognitive Impairment in Low and Middle-Income Countries: A Systematic Review
| Autor: | Ayesha Sajjad, Matthew Prina, Blossom C. M. Stephan, Devi Mohan, Louise Robinson, C Richardson, Yueping Zhu, Carla van Aller, Shulin Chen, Yee Chang Soh, Stella-Maria Paddick, Mario Siervo, Andrea McGrattan |
|---|---|
| Přispěvatelé: | Erasmus School of Health Policy & Management |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Population MEDLINE PsycINFO Disease behavioral disciplines and activities 03 medical and health sciences 0302 clinical medicine SDG 3 - Good Health and Well-being Risk Factors Environmental health mental disorders Epidemiology Prevalence medicine Humans Dementia Cognitive Dysfunction 030212 general & internal medicine Social isolation education Developing Countries Aged education.field_of_study business.industry General Neuroscience Cognition General Medicine Middle Aged medicine.disease Psychiatry and Mental health Clinical Psychology Geriatrics and Gerontology medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Alzheimer's Disease, 79(2), 743-762. IOS Press BV |
| ISSN: | 1875-8908 1387-2877 |
| DOI: | 10.3233/jad-201043 |
| Popis: | Background: Mild cognitive impairment (MCI) is a cognitive state associated with increased risk of dementia. Little research on MCI exists from low-and middle-income countries (LMICs), despite high prevalence of dementia in these settings. Objective: This systematic review aimed to review epidemiological reports to determine the prevalence of MCI and its associated risk factors in LMICs. Methods: Medline, Embase, and PsycINFO were searched from inception until November 2019. Eligible articles reported on MCI in population or community-based studies from LMICs and were included as long as MCI was clearly defined. Results: 5,568 articles were screened, and 78 retained. In total, n = 23 different LMICs were represented; mostly from China (n = 55 studies). Few studies were from countries defined as lower-middle income (n = 14), low income (n = 4), or from population representative samples (n = 4). There was large heterogeneity in how MCI was diagnosed; with Petersen criteria the most commonly applied (n = 26). Prevalence of amnesic MCI (aMCI) (Petersen criteria) ranged from 0.6%to 22.3%. Similar variability existed across studies using the International Working Group Criteria for aMCI (range 4.5%to 18.3%) and all-MCI (range 6.1%to 30.4%). Risk of MCI was associated with demographic (e.g., age), health (e.g., cardio-metabolic disease), and lifestyle (e.g., social isolation, smoking, diet and physical activity) factors. Conclusion: Outside of China, few MCI studies have been conducted in LMIC settings. There is an urgent need for population representative epidemiological studies to determine MCI prevalence in LMICs. MCI diagnostic methodology also needs to be standardized. This will allow for cross-study comparison and future resource planning. |
| Databáze: | OpenAIRE |
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