Updates on HIV nonoccupational postexposure prophylaxis
| Autor: | Adam Bullock, Lauren Middlebrooks, Atsuko Koyama |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Anti-HIV Agents business.industry Human immunodeficiency virus (HIV) MEDLINE HIV Infections medicine.disease_cause 03 medical and health sciences 0302 clinical medicine 030225 pediatrics 030220 oncology & carcinogenesis Family medicine Pediatrics Perinatology and Child Health medicine Humans Lack of knowledge Dosing Medical prescription Young adult Post-Exposure Prophylaxis business Hiv resistance |
| Zdroj: | Current Opinion in Pediatrics. 31:454-461 |
| ISSN: | 1040-8703 |
| DOI: | 10.1097/mop.0000000000000775 |
| Popis: | Purpose of review Adolescents and young adults continue to contribute to new HIV infections despite improved antiretroviral regimens and HIV preexposure and postexposure prophylaxis (PrEP and PEP). Knowledge about nonoccupational HIV PEP (nPEP) is relevant and important for all pediatricians as adolescents present under a variety of circumstances disclosing past sexual activity. Recent findings nPEP is effective in preventing HIV infection, and newer regimens have been shown to increase compliance amongst users, have less side effects, and lead to less HIV resistance. Yet, research on physician prescription practices shows a lack of knowledge regarding appropriate HIV nPEP medication regimens, dosing, and follow-up recommendations. Updated national guidelines are available to providers who may be unfamiliar with indications and drug regimens for nPEP. Studies also provide different strategies to increase nPEP use and compliance among patients as well as ways to increase provider awareness of appropriate nPEP prescription. Summary Research of HIV nPEP shows that it is effective when used correctly, but there needs to be increased education and awareness to increase provider prescription and patient use as well as institutional changes to help patients complete the full course of medication. |
| Databáze: | OpenAIRE |
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