InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium
| Autor: | Siegfried Hapfelmeier, Wolf-Dietrich Hardt, Kristin Ehrbar, Bärbel Stecher |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Salmonella typhimurium
Molecular Biology of Pathogens Salmonella biology Transcription Genetic Effector animal diseases biochemical phenomena metabolism and nutrition biology.organism_classification medicine.disease_cause Microbiology Enterobacteriaceae Type three secretion system Transport protein Protein Transport Cytosol Bacterial Proteins Salmonella enterica Chaperone (protein) biology.protein medicine bacteria Secretion Molecular Biology |
| Zdroj: | Journal of bacteriology. 186(4) |
| ISSN: | 0021-9193 |
| Popis: | The Salmonella effector protein SopA is translocated into host cells via the SPI-1 type III secretion system (TTSS) and contributes to enteric disease. We found that the chaperone InvB binds to SopA and slightly stabilizes it in the bacterial cytosol and that it is required for its transport via the SPI-1 TTSS. |
| Databáze: | OpenAIRE |
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