Rhinovirus C Is Associated With Severe Wheezing and Febrile Respiratory Illness in Young Children
| Autor: | Riku Erkkola, Kati Räisänen, Miia K. Laine, Tytti Vuorinen, Paula A. Tähtinen, James E. Gern, Riitta Turunen, Tuomas Jartti, Yury A. Bochkov, Matti Waris, Aino Ruohola |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Microbiology (medical) medicine.medical_specialty Fever Rhinovirus viruses medicine.disease_cause Article 03 medical and health sciences 0302 clinical medicine stomatognathic system 030225 pediatrics Internal medicine Wheeze medicine Humans Prospective Studies 030212 general & internal medicine Prospective cohort study Respiratory Tract Infections Finland Enterovirus Respiratory Sounds Retrospective Studies Picornaviridae Infections business.industry Infant virus diseases Retrospective cohort study Common cold respiratory system medicine.disease respiratory tract diseases 3. Good health Infectious Diseases medicine.anatomical_structure Bronchiolitis Child Preschool Pediatrics Perinatology and Child Health Female medicine.symptom business Respiratory tract Cohort study |
| Zdroj: | Pediatr Infect Dis J |
| ISSN: | 0891-3668 |
| Popis: | Background Rhinovirus is the most common virus causing respiratory tract illnesses in children. Rhinoviruses are classified into species A, B and C. We examined the associations between different rhinovirus species and respiratory illness severity. Methods This is a retrospective observational cohort study on confirmed rhinovirus infections in 134 children 3-23 months of age, who were enrolled in 2 prospective studies on bronchiolitis and acute otitis media, respectively, conducted simultaneously in Turku University Hospital, Turku, Finland, between September 2007 and December 2008. Results Rhinovirus C is the most prevalent species in our study, and it was associated with severe wheezing and febrile illness. We also noted that history of atopic eczema was associated with wheezing. Conclusions Our understanding of rhinovirus C as the most pathogenic rhinovirus species was fortified. Existing research supports the idea that atopic characteristics are associated with the severity of the rhinovirus C-induced illness. |
| Databáze: | OpenAIRE |
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