Early postoperative MRI overestimates residual tumour after resection of gliomas with no or minimal enhancement
| Autor: | Jan J. Heimans, W. Peter Vandertop, Philip C. De Witt Hamer, Sinan M. K. Belhawi, Frederik Barkhof, Jaap C. Reijneveld, Johannes C. Baaijen, Friso W. A. Hoefnagels, Esther Sanchez Aliaga |
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| Přispěvatelé: | Neurosurgery, Neurology, Amsterdam Neuroscience, Faculteit der Geneeskunde, CCA - Innovative therapy, Radiology and nuclear medicine, CCA - Disease profiling, CCA - Quality of life, NCA - Brain Imaging, NCA - Childhood White Matter Diseases, NCA - Multiple Sclerosis and Other Neuroinflammatory Diseases, NCA - Neurodegeneration, Amsterdam Neuroscience - Neurovascular Disorders |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Neoplasm Residual Diffusion magnetic resonance imaging Contrast Media Postoperative mri Residual Statistics Nonparametric Resection Glioma Diagnostic techniques and procedures medicine Humans Radiology Nuclear Medicine and imaging Postoperative Period Neuroradiology Retrospective Studies medicine.diagnostic_test business.industry Brain Neoplasms Ultrasound Brain Magnetic resonance imaging Interventional radiology General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Radiology Nuclear Medicine and imaging Linear Models Neurosurgical procedures Female Radiology Neuro business |
| Zdroj: | European Radiology European radiology, 21(7), 1526-1534. Springer Verlag European Radiology, 21(7), 1526-1534. Springer Verlag Belhawi, S M K, Hoefnagels, F W A, Baaijen, J C, Aliaga, E S, Reijneveld, J C, Heimans, J J, Barkhof, F, Vandertop, W P & Hamer, P C D W 2011, ' Early postoperative MRI overestimates residual tumour after resection of gliomas with no or minimal enhancement ', European Radiology, vol. 21, no. 7, pp. 1526-1534 . https://doi.org/10.1007/s00330-011-2081-y |
| ISSN: | 0938-7994 |
| DOI: | 10.1007/s00330-011-2081-y |
| Popis: | BACKGROUND: Standards for residual tumour measurement after resection of gliomas with no or minimal enhancement have not yet been established. In this study residual volumes on early and late postoperative T2-/FLAIR-weighted MRI are compared.METHODS: A retrospective cohort included 58 consecutive glioma patients with no or minimal preoperative gadolinium enhancement. Inclusion criteria were first-time resection between 2007 and 2009 with a T2-/FLAIR-based target volume and availability of preoperative, early (RESULTS: Residual tumour volumes were 22% smaller on late postoperative compared with early postoperative T2-weighted MRI and 49% smaller for FLAIR-weighted imaging. Postoperative restricted diffusion volume correlated with the difference between early and late postoperative FLAIR volumes and with the difference between T2 and FLAIR volumes on early postoperative MRI.CONCLUSION: We observed a systematic and substantial overestimation of residual non-enhancing volume on MRI within 48 h of resection compared with months postoperatively, in particular for FLAIR imaging. Resection-induced ischaemia contributes to this overestimation, as may other operative effects. This indicates that early postoperative MRI is less reliable to determine the extent of non-enhancing residual glioma and restricted diffusion volumes are imperative. |
| Databáze: | OpenAIRE |
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