Dependency on Acid-base Status of Oxyhemoglobin Dissociation and 2, 3-Diphosphoglycerate Level in Human Erythrocytes: II. In Vivo Studies
| Autor: | C. Thorshauge, P. Astrup, M. Rörth |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Acid-Base Equilibrium
Erythrocytes Red Cell Clinical Biochemistry chemistry.chemical_element General Medicine Acid–base homeostasis Hydrogen-Ion Concentration Oxygen Phosphates Hemoglobins chemistry Biochemistry In vivo Glycerophosphates Humans Hemoglobin Acid–base reaction Diphosphoglycerate Hypoxia Oxyhemoglobin dissociation |
| Zdroj: | Scandinavian Journal of Clinical and Laboratory Investigation. 26:47-52 |
| ISSN: | 1502-7686 0036-5513 |
| DOI: | 10.3109/00365517009049213 |
| Popis: | The intraerythrocytic level of 2,3-diphosphoglycerate and the oxygen affinity of hemoglobin in the red cell are shown to be strongly dependent on the intraerythrocytic pH. This effect should be taken into account when evaluating the increase in 2,3-diphosphoglycerate found at hypoxemic and anemic hypoxia. It was also demonstrated that high concentrations of inorganic phosphate in serum influence the intraerythrocytic 2,3-diphosphoglycerate concentration. |
| Databáze: | OpenAIRE |
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