Asymmetric trifluoromethylthiolation of azlactones under chiral phase transfer catalysis
Autor: | Giorgio Della Sala, Rafael Cano, Vito Capaccio, Marina Sicignano, José Alemán, Luca Bernardi, Francesco De Riccardis, Sergio Díaz-Tendero, Ricardo I. Rodríguez, Fabio Borello |
---|---|
Přispěvatelé: | UAM. Departamento de Química, UAM. Departamento de Química Orgánica, Sicignano M., Rodriguez R.I., Capaccio V., Borello F., Cano R., De Riccardis F., Bernardi L., Diaz-Tendero S., Della Sala G., Aleman J. |
Rok vydání: | 2020 |
Předmět: |
Chemistry
Organic Chemistry Enantioselective synthesis Quinidinium Chiral phase Química Azlactone Biochemistry Electron Catalysis Phase-Transfer Catalysi Transfer (group theory) Computational chemistry Phase (matter) Trifluormethylthiolation Asymmetric synthesi Physical and Theoretical Chemistry Aryl groups |
Zdroj: | Biblos-e Archivo: Repositorio Institucional de la UAM Universidad Autónoma de Madrid Biblos-e Archivo. Repositorio Institucional de la UAM instname |
ISSN: | 2018-0950 |
Popis: | The first enantioselective method for the installation of the SCF3 group at the C-4 position of azlactones is described in the present communication under quinidinium phase transfer catalysis. The higher performance of substrates containing electron-rich 2-aryl groups at the azlactone was rationalized using DFT calculations We are grateful to the Spanish Government (RTI2018-095038-B-I00, CTQ, CTQ2016-76061-P), “Comunidad de Madrid” and European Structural Funds (S2018/NMT-4367) |
Databáze: | OpenAIRE |
Externí odkaz: |
načítá se...