B-cell neurolymphomatosis confined to the peripheral nervous system
| Autor: | Miharu Samuraki, Ayumi Shibata-Hamaguchi, Eisuke Furui, Masahito Yamada, Hiroshi Minato, Shinji Nakao, Satoshi Kitagawa, Chiho Ishida |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Nervous system
Lymphoma B-Cell Nerve root Central nervous system Fatal Outcome medicine Humans Neoplasm Invasiveness Peripheral Nerves Aged B-Lymphocytes Plexus business.industry Cranial nerves Cranial Nerves Peripheral Nervous System Diseases Anatomy Disseminated Intravascular Coagulation medicine.disease Cranial Nerve Diseases Peripheral neuropathy medicine.anatomical_structure Neurology Peripheral nervous system Disease Progression Female Neurology (clinical) Spinal Nerve Roots business Polyneuropathy |
| Zdroj: | Journal of the Neurological Sciences. 260:249-252 |
| ISSN: | 0022-510X |
| DOI: | 10.1016/j.jns.2007.03.029 |
| Popis: | Patients with neurolymphomatosis show lymphoma cells within the peripheral nerves, nerve root/plexus, or cranial nerves. However, most neurolymphomatosis patients show lymphomatous infiltration not only in the peripheral nervous system (PNS), but also in the meninges, Virchow-Robin space, and brain parenchyma. Here, we report a 74-year-old woman with diffuse large B-cell lymphoma presenting with motor-sensory-autonomic polyneuropathy and multiple cranial neuropathies. A diagnosis of neurolymphomatosis was made by sural nerve biopsy. Postmortem examination indicated that lymphoma cell infiltration in the nervous system was confined to the PNS with no involvement of the central nervous system, including the meninges. This was a very rare case of B-cell neurolymphomatosis with lymphomatous infiltration confined to the PNS, suggesting specific affinity of the lymphoma cells for the PNS in this patient. |
| Databáze: | OpenAIRE |
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