Cerebellar hyperperfusion in semantic dementia
| Autor: | Stefano Diciotti, Alessandra Vella, Riccardo Della Nave, Fabrizio Banci Bonamici, Roberto Vetrugno, Stefania Boschi, Mario Mascalchi |
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| Přispěvatelé: | Vella A, Della Nave R, Vetrugno R, Diciotti S, Boschi S, Banci Bonamici F, Mascalchi M |
| Rok vydání: | 2013 |
| Předmět: |
Male
Cerebellum cerebellum Semantic dementia Statistical parametric mapping Text mining Arts and Humanities (miscellaneous) Region of interest PERFUSION medicine Humans Neurodegeneration Aged Aged 80 and over Tomography Emission-Computed Single-Photon language business.industry Parietal lobe Middle Aged medicine.disease Temporal Lobe Aphasia Primary Progressive medicine.anatomical_structure Frontotemporal Dementia SPECT Female Neurology (clinical) Psychology business Neuroscience Perfusion |
| Zdroj: | Neurocase. 20:175-182 |
| ISSN: | 1465-3656 1355-4794 |
| DOI: | 10.1080/13554794.2012.741255 |
| Popis: | Despite evidence of a cerebellar contribution to language, possible functional changes of the cerebellum in patients with language impairment secondary to cerebral neurodegeneration has not been investigated so far. We examined with resting perfusion single photon emission tomography one patient with semantic dementia and the data were compared with a normal subject database. Region of interest and Statistical Parametric Mapping 2 analysis showed in the patient hypoperfusion of the left temporal and parietal lobe and hyperperfusion in the superior vermis and cerebellar hemispheres (lobules IV, V, and VI). The cerebellum shows increased flow of possible compensatory significance in patients with language disturbance associated to cerebral degenerative changes. |
| Databáze: | OpenAIRE |
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