Structural brain features of borderline personality and bipolar disorders

Autor: Michela Pievani, Giovanni B. Frisoni, Laura R Magni, Marco Lorenzi, Stefano Bignotti, Roberta Rossi, Sandra Rosini, Panteleimon Giannakopoulos, Marina Boccardi, Luciana Rillosi, Maria Cotelli, Genoveffa Borsci, Rossella Beneduce, Giuseppe Rossi
Přispěvatelé: Unit of Psychiatry [Brescia], IRCCS Fatebenefratelli - Brescia, Neuroimaging and Telemedicine (LENITEM), Analysis and Simulation of Biomedical Images (ASCLEPIOS), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Neuropsychological Unit [Brescia], IRCCS San Giovanni di Dio Fatebenefratelli, Department of psychiatry, Geneva University Hospital (HUG), Asclepios, Project-Team
Rok vydání: 2013
Předmět:
Adult
Male
Pathology
medicine.medical_specialty
Bipolar Disorder
[INFO.INFO-IM] Computer Science [cs]/Medical Imaging
Neuroscience (miscellaneous)
Neuroimaging
computer.software_genre
Statistical parametric mapping
Nerve Fibers
Myelinated

behavioral disciplines and activities
White matter
ddc:616.89
Borderline Personality Disorder
Voxel
Region of interest
mental disorders
Bipolar Disorder/pathology
[INFO.INFO-IM]Computer Science [cs]/Medical Imaging
medicine
Humans
Brain/pathology
Radiology
Nuclear Medicine and imaging

Bipolar disorder
Psychiatry
Borderline personality disorder
Nerve Fibers
Unmyelinated

Nerve Fibers
Myelinated/pathology

Brain
Nerve Fibers
Unmyelinated/pathology

Voxel-based morphometry
medicine.disease
Magnetic Resonance Imaging
Atrophy/pathology
Psychiatry and Mental health
medicine.anatomical_structure
Borderline Personality Disorder/pathology
Case-Control Studies
Female
Atrophy
Psychology
computer
Zdroj: Psychiatry Research: Neuroimaging
Psychiatry Research: Neuroimaging, 2012, 12, pp.83-91
Psychiatry Research, Vol. 213, No 2 (2013) pp. 83-91
ISSN: 0925-4927
1872-7506
0165-1781
Popis: International audience; A potential overlap between bipolar disorder (BD) and borderline personality disorder (BPD) has been recently proposed. We aimed to assess similarities and differences of brain structural features in BD and BPD. Twenty-six in-patients with BPD, 14 with BD and 40 age and sex-matched healthy controls (HC) underwent structural magnetic resonance (MR). Voxel-based morphometry analysis with Statistical Parametric Mapping (SPM) was used to localize and quantify gray (GM) and white matter (WM) abnormalities in BD and BPD compared to HC and to identify those specifically affected in each patient group (p
Databáze: OpenAIRE