Adding marrow R2∗ to proton density fat fraction improves the discrimination of osteopenia and osteoporosis in postmenopausal women assessed with 3D FACT sequence
| Autor: | Xuefeng Li, Xiaoyong Zuo, Shixin Chang, Guanwu Li, Yongming Dai, Zheng Xu, Dongmei Wu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Bone density
Intraclass correlation General Mathematics Coefficient of variation Osteoporosis 030209 endocrinology & metabolism 03 medical and health sciences 0302 clinical medicine Bone Marrow medicine Humans 030219 obstetrics & reproductive medicine Receiver operating characteristic business.industry Applied Mathematics Obstetrics and Gynecology Reproducibility of Results medicine.disease Magnetic Resonance Imaging Confidence interval Osteopenia Postmenopause Bone Diseases Metabolic Adipose Tissue Female Protons business Nuclear medicine Body mass index |
| Zdroj: | Menopause (New York, N.Y.). 28(7) |
| ISSN: | 1530-0374 |
| Popis: | OBJECTIVE To evaluate the role of three-dimensional Fat Analysis & Calculation Technique sequence in improving the diagnostic accuracy for the detection of osteopenia and osteoporosis by simultaneous quantification of proton density fat fraction (PDFF) and fat-corrected R2∗. METHODS Fat Analysis & Calculation Technique imaging of lumbar spine was obtained in 99 postmenopausal women including 52 normal bone mass, 29 osteopenia, and 18 osteoporosis. The diagnostic performance of PDFF and R2∗ in the differentiation of different bone-density groups was evaluated with the receiver operating characteristic curve. RESULTS The reproducibility of PDFF and R2∗ measures was satisfactory with the root mean square coefficient of variation, 2.16% and 2.70%, respectively. The intra- and interobserver agreements for the PDFF and R2∗ were excellent with the intraclass correlation coefficient > 0.9 for all. There were significant differences in PDFF and R2∗ among the three groups (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|