Assessment of Subclinical Psychotic Symptoms in Patients with Rheumatoid Arthritis and Spondyloarthritis
| Autor: | Juan L Prados-Ojeda, Alejandro Escudero-Contreras, Eduardo Collantes-Estevez, Ipek Guler, Clementina López-Medina, Rafael M Gordillo-Urbano, Rogelio Luque-Luque |
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| Přispěvatelé: | [Prados-Ojeda,JL, Luque-Luque,R, Gordillo-Urbano,RM] Mental Health Department, Reina Sofia University Hospital, Cordoba, Spain. [Prados-Ojeda,JL, Luque-Luque,R] Morphological and Socio-Sanitary Sciences, University of Cordoba, Cordoba, Spain. [Prados-Ojeda,JL, Guler,I, López-Medina,C, Collantes-Estévez,E, Escudero-Contreras,A] Maimonides Institute of Biomedical Research of Córdoba (IMIBIC), Cordoba, Spain. [López-Medina,C, Escudero-Contreras,A] Medical and Surgical Sciences Department, University of Cordoba, Cordoba, Spain. [López-Medina,C, Escudero-Contreras,A] Rheumatology Department, Reina Sofia University Hospital, Cordoba, Spain. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
rheumatoid arthritis
Espondiloartritis axial Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] 0302 clinical medicine Manifestaciones neurológicas Depresión Diseases::Musculoskeletal Diseases::Bone Diseases::Spinal Diseases::Spondylitis::Spondylarthritis [Medical Subject Headings] Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence [Medical Subject Headings] Depression (differential diagnoses) Subclinical infection education.field_of_study autoimmunity General Medicine spondyloarthritis anxiety Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings] Distress Diseases::Musculoskeletal Diseases::Rheumatic Diseases::Arthritis Rheumatoid [Medical Subject Headings] psychotic symptoms Rheumatoid arthritis Diseases::Musculoskeletal Diseases::Rheumatic Diseases [Medical Subject Headings] depression Anxiety Medicine medicine.symptom medicine.medical_specialty Population Autoinmunidad Artritis reumatoide Article 03 medical and health sciences Ansiedad Internal medicine medicine Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Psychotic Disorders [Medical Subject Headings] education Psychiatry and Psychology::Behavior and Behavior Mechanisms::Emotions::Anxiety [Medical Subject Headings] Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys [Medical Subject Headings] Inflamación business.industry medicine.disease Comorbidity 030227 psychiatry inflammation Etiology business Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Behavioral Symptoms::Depression [Medical Subject Headings] Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Inflammation [Medical Subject Headings] 030217 neurology & neurosurgery |
| Zdroj: | Journal of Clinical Medicine Volume 10 Issue 16 Journal of Clinical Medicine 10(16), 3461 (2021) Helvia. Repositorio Institucional de la Universidad de Córdoba instname Journal of Clinical Medicine, Vol 10, Iss 3461, p 3461 (2021) |
| Popis: | Inflammatory and autoimmune processes have been associated with the onset of depressive and psychotic symptoms. Rheumatoid arthritis (RA) and spondyloarthritis (SpA) are rheumatic diseases with an inflammatory etiology. A high prevalence of depressive and anxiety-related comorbidity has been reported for both diseases, with no evidence of a greater prevalence of psychosis. The objective of the present study was to evaluate for the first time subclinical psychotic symptoms in patients with RA and SpA. This is a cross-sectional, single-center study including RA and SpA patients, as well as healthy controls. Abnormal psychotic experiences (positive, negative, and depressive symptoms) were evaluated using the Community Assessment of Psychic Experiences (CAPE-42). Functional capacity was evaluated using the Short-Form Health Survey SF-12. We compared the CAPE and SF-12 scores between the three groups. We recruited 385 individuals: 218 with RA, 100 with SpA, and 67 healthy controls. According to the CAPE scale, the frequency of subclinical psychotic symptoms was greater in patients than in healthy controls (RA, 1.90 vs. 1.63, p < 0.001 SpA, 1.88 vs. 1.63, p = 0.001). Distress was also greater in patients than in controls owing to the presence of symptoms. No differences were observed between the three groups for the mental dimension scores in the SF-12 Health Survey (43.75 in RA, 45.54 in SpA, and 43.19 in healthy controls). Our findings point to a greater prevalence of subclinical psychotic symptoms in patients with RA and patients with SpA than in the general population. The results suggest an association between inflammation and depression/subclinical psychotic symptoms. |
| Databáze: | OpenAIRE |
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