Skeletal muscle mass and exercise performance in stable ambulatory patients with heart failure
| Autor: | John R. Wilson, Chim C. Lang, Tiong-Keat Yeoh, Glenn Rayos, Don Chomsky |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart disease Physiology Physical fitness Physical exercise Body Mass Index Age Distribution Physiology (medical) Internal medicine Humans Medicine Exercise physiology Muscle Skeletal Exercise Heart Failure business.industry Middle Aged medicine.disease Heart failure Ambulatory Physical therapy Lean body mass Cardiology Female business Body mass index |
| Zdroj: | Journal of Applied Physiology. 82:257-261 |
| ISSN: | 1522-1601 8750-7587 |
| Popis: | Lang, Chim C., Don B. Chomsky, Glenn Rayos, T. K. Yeoh, and John R. Wilson. Skeletal muscle mass and exercise performance in stable ambulatory patients with heart failure. J. Appl. Physiol. 82(1): 257–261, 1997.—The purpose of this study was to determine whether skeletal muscle atrophy limits the maximal exercise capacity of stable ambulatory patients with heart failure. Body composition and maximal exercise capacity were measured in 100 stable ambulatory patients with heart failure. Body composition was assessed by using dual-energy X-ray absorption. Peak exercise oxygen consumption (V˙o 2 peak) and the anaerobic threshold were measured by using a Naughton treadmill protocol and a Medical Graphics CardioO2 System.V˙o 2 peak averaged 13.4 ± 3.3 ml ⋅ min−1 ⋅ kg−1or 43 ± 12% of normal. Lean body mass averaged 52.9 ± 10.5 kg and leg lean mass 16.5 ± 3.6 kg. Leg lean mass correlated linearly with V˙o 2 peak( r= 0.68, P < 0.01), suggesting that exercise performance is influenced by skeletal muscle mass. However, lean body mass was comparable to levels noted in 1,584 normal control subjects, suggesting no decrease in muscle mass. Leg muscle mass was comparable to levels noted in 34 normal control subjects, further supporting this conclusion. These findings suggest that exercise intolerance in stable ambulatory patients with heart failure is not due to skeletal muscle atrophy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|