Rizični čimbenici i koštana masa u bolesnika s recidivirajućom urolitijazom: presječno istraživanje na 144 ispitanika

Autor: Ivana Marić, Tomislav Kizivat, Ivan Mihaljević, Martina Smolić, Jasminka Milas Ahić, Robert Smolić, Krešimir Šolić, Antun Tucak, Hrvoje Roguljić, Teuta Opačak-Bernardi
Rok vydání: 2020
Předmět:
urolithiasis
bone mineral density
body weight
body mass index
physical activity
smoking
calcium intake
Male
030213 general clinical medicine
0209 industrial biotechnology
medicine.medical_specialty
Cross-sectional study
Croatia
02 engineering and technology
03 medical and health sciences
020901 industrial engineering & automation
0302 clinical medicine
Absorptiometry
Photon
Urolithiasis
Bone Density
Risk Factors
Internal medicine
Surveys and Questionnaires
Medicine
Humans
Recurrent stone
Hypercalciuria
Original Scientific Papers
Life Style
Sedentary lifestyle
2. Zero hunger
Bone mineral
Calcium stone
business.industry
Smoking
General Medicine
Feeding Behavior
Middle Aged
medicine.disease
3. Good health
Calcium
Dietary
urolitijaza
mineralna gustoća kosti
tjelesna težina
indeks tjelesne mase
tjelesna aktivnost
pušenje
unos kal-cija
Cross-Sectional Studies
Female
business
Body mass index
Bone mass
Zdroj: Acta clinica Croatica
Volume 58.
Issue 3.
Acta Clinica Croatica
ISSN: 1333-9451
0353-9466
Popis: Patients with urolithiasis, particularly hypercalciuria, may have reduced bone mineral density (BMD). There are numerous risk factors contributing to reduction of BMD such as advanced age, sedentary life-style, smoking, low calcium intake, etc. The aim of our study was to investigate the association of lifestyle risk factors and daily intake of milk and dairy products with determinants of BMD in a group of recurrent calcium stone formers (RSF) compared with healthy subjects (HS). The study was carried out at the De-partment of Mineral Research, Faculty of Medicine in Osijek, Croatia. The study included 144 subjects, i.e. 56 RSF and 78 HS. BMD was assessed by dual-energy x-ray absorptiometry. A standard self-reported questionnaire was used to collect data on lifestyle risk factors. Current dietary intake was assessed by personal interview that included questions about milk and dairy product intake. Low BMD was observed in 44.64% of RSF and 35.90% of HS. RSF consumed significantly less milk and dairy products than HS. Calcium restriction in dietary recommendations might be unnecessary due to the impact on bone mineral loss in RSF and dual-energy x-ray absorptiometry should be included in the routine evaluation of RSF.
Bolesnici s urolitijazom, osobito oni s hiperkalciurijom, imaju smanjenu koštanu mineralnu gustoću (bone mineral density, BMD). Rizični čimbenici gubitka koštane mase su uznapredovala dob, sjedilački način života, pušenje i smanjen unos kalcija. Cilj našeg istraživanja bio je ustanoviti povezanost rizičnih čimbenika i dnevnog unosa mlije-ka i mliječnih prerađevina s odrednicama BMD u bolesnika s recidivirajućom kalcijskom urolitijazom te ih usporedi-ti sa zdravim ispitanicima. Istraživanje je provedeno na Zavodu za mineralni metabolizam Medicinskog fakulteta u Osijeku. U istraživanju su sudjelovala 144 ispitanika, od čega 56 bolesnika s recidivirajućom kalcijskom urolitija-zom i 78 zdravih ispitanika. BMD je određen metodom dvoenergetske apsorpciometrije X zraka (DXA). Podatci o čimbenicima rizika dobiveni su anketnim upitnikom, a unos hrane je ocijenjen osobnim intervjuom koji je uključi-vao pitanja o unosu mlijeka i mliječnih proizvoda. Snižen BMD zabilježen je u 44,64% bolesnika s recidivirajućom urolitijazom i u 35,90% zdravih ispitanika. Bolesnici s recidivirajućom urolitijazom konzumirali su znatno manje mlijeka i mliječnih proizvoda u odnosu na zdrave ispitanike. Nepotrebna je preporuka smanjenog unosa kalcija bolesnicima s recidivirajućom urolitijazom zbog utjecaja na gubitak koštane mase, a DXA treba biti dio rutinske procjene bolesnika s recidivirajućom urolitijazom.
Databáze: OpenAIRE
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