EFFECT OF ANAESTHESIA ON OVARIAN FOLLICULAR DEVELOPMENT AND OVULATION IN THE SHEEP SUBSEQUENT TO PROSTAGLANDIN-INDUCED LUTEOLYSIS
| Autor: | J. K. Findlay, C. D. Nancarrow, H. M. Radford |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Ovulation
medicine.medical_specialty Endocrinology Diabetes and Metabolism media_common.quotation_subject Luteolysis Prostaglandin Luteal phase chemistry.chemical_compound Endocrinology Estrus Ovarian Follicle Pregnancy Internal medicine Follicular phase medicine Animals Anesthesia Ovarian follicle Pentobarbital media_common Estrous cycle Sheep Chemistry Cloprostenol Antral follicle medicine.anatomical_structure Prostaglandins F Synthetic Female Estrus Synchronization |
| Zdroj: | Journal of Endocrinology. 78:321-327 |
| ISSN: | 1479-6805 0022-0795 |
| DOI: | 10.1677/joe.0.0780321 |
| Popis: | Prostaglandin analogues were used to induce luteal regression simultaneously in a number of ewes, thereby synchronizing the final stages of follicular maturation in these animals. Some of the ewes were anaesthetized for 24 h immediately after the injection of prostaglandin (experiment 1), and others for 15 h, starting 24 h after the injection of prostaglandin (experiment 2). In both experiments administration of anaesthetic significantly delayed the onset of oestrus and the time of ovulation relative to prostaglandin-treated control animals. The results from assays of blood samples collected at regular intervals in experiment 1 indicated that the preovulatory peak in the concentration of LH and the periovulatory changes in the concentration of FSH were similarly delayed and that during anaesthesia the level of LH was significantly reduced. It is suggested that the reduced level of LH, which probably resulted from a reduction in the secretion of releasing factor due to anaesthesia, failed to support oestrogen production by the Graafian follicle(s), thereby delaying the occurrence of oestrus and ovulation. |
| Databáze: | OpenAIRE |
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