Meta-analysis of transanal total mesorectal excision versus laparoscopic total mesorectal excision in management of rectal cancer
| Autor: | Howard Joy, Rajeev Peravali, Mokhtar Eltair, Shahin Hajibandeh, Anil T George, Misra Budhoo, Vijay Thumbe, Andrew W. Torrance, Shahab Hajibandeh |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Risk medicine.medical_specialty Time Factors Colorectal cancer Anal Canal Anastomotic Leak 030230 surgery Anastomosis 03 medical and health sciences Postoperative Complications 0302 clinical medicine Internal medicine medicine Humans Surgical Wound Infection Clinical significance Intraoperative Complications Aged Mesorectal Rectal Neoplasms business.industry Rectum Gastroenterology Middle Aged Hepatology medicine.disease Conversion to Open Surgery Total mesorectal excision Surgery Observational Studies as Topic 030220 oncology & carcinogenesis Meta-analysis Female Laparoscopy Circumferential resection margin Lymph Nodes business Publication Bias |
| Zdroj: | International Journal of Colorectal Disease. 35:575-593 |
| ISSN: | 1432-1262 0179-1958 |
| DOI: | 10.1007/s00384-020-03545-7 |
| Popis: | To evaluate comparative outcomes of transanal total mesorectal excision (TaTME) and laparoscopic TME (LaTME) in patients with rectal cancer. We systematically searched multiple databases and bibliographic reference lists. A combination of free text and controlled vocabulary search adapted to thesaurus headings, search operators, and limits were applied. Overall intraoperative complications, overall postoperative complications, anastomotic leak, surgical site infections (SSIs), completeness of mesorectal excision, R0 resection, distal (DRM) and circumferential resection margin (CRM), number of harvested lymph nodes, and procedure time were the evaluated outcome parameters. We identified 18 comparative studies reporting a total of 2048 patients evaluating outcomes of TaTME (n = 1000) and LaTME (n = 1048) in patients with rectal cancer. TaTME was associated with significantly higher number of R0 resection (OR 1.67, P = 0.01) and harvested lymph nodes (MD 1.08, P = 0.01), and lower rate of positive CRM (OR 0.67, P = 0.04) and conversion to an open procedure (OR 0.17, P |
| Databáze: | OpenAIRE |
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