| Autor: |
Kensuke Kojima, Gwen Nichols, Jianguo Zhi, Ruediger Rueger, Monica Reckner, Steve Middleton, Lori Jukofsky, Peter Bridge, Steven Blotner, Bradford Graves, Gong Chen, Xuelin Huang, Graciela M. Nogueras González, Vivian Ruvolo, Swaminathan Padmanabhan Iyer, Mark Kirschbaum, Paresh Vyas, Mark W. Drummond, Giovanni Martinelli, David Bowen, Leslie Popplewell, Roger Strair, Sarit Assouline, Karen Yee, Kevin R. Kelly, Michael Andreeff |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1078-0432.22460694.v1 |
| Popis: |
Supplementary Table 1. Study stratification and dosing regimen; Supplementary Table 2. p53 target genes examined in this study; Supplementary Table 3. Characteristics of evaluable patients treated at the MTD; Supplementary Table 4. Patient demographic data by cohort; Supplementary Table 5. Adverse events by grade observed in > 10% of the patients/stratum; Supplementary Table 6. Stratum pharmacokinetic parameters based on RG7112 dose regimen and formulation; Supplementary Table 7. Summary of steady state AUC for AML patients treated at the MTD; Supplementary Table 8. Clinical activity for patients with p53 mutations |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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