Very-Rapidly Dissolving Printlets of Isoniazid Manufactured by SLS 3D Printing: In Vitro and In Vivo Characterization
Autor: | Tahir Khuroo, Eman M. Mohamed, Sathish Dharani, Canberk Kayalar, Tanil Ozkan, Mathew A. Kuttolamadom, Ziyaur Rahman, Mansoor A. Khan |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Molecular Pharmaceutics. 19:2937-2949 |
ISSN: | 1543-8392 1543-8384 |
Popis: | The focus of this research was to understand the effects of formulation and processing variables on the very-rapidly dissolving printlets of isoniazid (INH) manufactured by the selective laser sintering (SLS) three-dimensional (3D) printing method, and to characterize their physicochemical properties, stability, and pharmacokinetics. Fifteen printlet formulations were manufactured by varying the laser scanning speed (400-500 mm/s |
Databáze: | OpenAIRE |
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