BIOCHEMICAL ANALYSIS AND BONE REMODELING IN RESPONSE TO OOPHORECTOMY AND AQUATIC TRAINING
| Autor: | Ana Paula Girol, Melina Mizusaki Iyomasa, Helena Ribeiro Souza, Mauricio Ferraz de Arruda, Adriana Paula Sanchez Schiaveto, Mairto Roberis Geromel |
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| Přispěvatelé: | Instituto Municipal de Ensino Superior de Catanduva (IMES-Catanduva), Faculdades Integradas Padre Albino (FIPA), Universidade Estadual Paulista (Unesp), Faculdade de Ciências da Saúde de Barretos Dr. Paulo Prata (FACISB) |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Oophorectomy medicine.medical_treatment Osteoporosis Osteoclasts chemistry.chemical_element 030209 endocrinology & metabolism Physical Therapy Sports Therapy and Rehabilitation Calcium Bone remodeling 03 medical and health sciences 0302 clinical medicine Osteoclast Internal medicine Alkaline phosphatase medicine Orthopedics and Sports Medicine Femur Exercise Swimming Orthopedic surgery business.industry Rehabilitation 030229 sport sciences Original Articles medicine.disease Rats Radiography medicine.anatomical_structure Endocrinology chemistry Medicine business Densitometry RD701-811 |
| Zdroj: | Acta Ortopedica Brasileira Acta Ortopédica Brasileira, Volume: 24, Issue: 5, Pages: 235-239, Published: OCT 2016 Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Acta Ortopédica Brasileira v.24 n.5 2016 Acta Ortopédica Brasileira Sociedade Brasileira de Ortopedia e Traumatologia (SBOT) instacron:SBOT Acta Ortopédica Brasileira, Vol 24, Iss 5, Pp 235-239 (2016) |
| ISSN: | 1413-7852 |
| Popis: | Made available in DSpace on 2018-12-11T16:44:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-01-01. Added 1 bitstream(s) on 2021-07-15T15:02:19Z : No. of bitstreams: 1 S1413-78522016000500235.pdf: 1256739 bytes, checksum: 43b5e5a7b157e8668cb2b8b6ceb08b24 (MD5) Objective: To investigate whether swimming could prevent bone loss and could be indicated to assist in treatment of osteoporosis. Methods: Female rats were divided into 4 groups (n=6), two of them were oophorectomized. Animals from two groups, one oophorectomized and another not oophorectomized, underwent aquatic training for eight weeks. After training, the animals were sacrificed and their blood was collected for calcium and alkaline phosphatase serum dosage; the femur was removed and subjected to radiological and histological densitometry analysis to assess bone loss and osteoclast counting on femoral head and neck. Results: Increase in serum calcium was not observed. There was an increasing activity of alkaline phosphatase in the oophorectomized groups. The radiographs suggest that there was a greater bone mass density in the trained groups. Concerning histology, the trained groups had better tissue structural organization than the sedentary groups. In the oophorectomized and sedentary group, higher presence of osteoclasts was observed a. Conclusion: Exercise and oophorectomy did not promote changes in serum calcium levels. The decrease of sex steroids caused by oophorectomy was responsible for severe bone loss, but swimming exercise was able to reduce this loss. Oophorectomy promoted the proliferation of osteoclasts and the exercise proved to be able to diminish it. Level of Evidence I, Experimental Study. Instituto Municipal de Ensino Superior de Catanduva (IMES-Catanduva) Faculdades Integradas Padre Albino (FIPA) Universidade Estadual Paulista (UNESP) Faculdade de Ciências da Saúde de Barretos Dr. Paulo Prata (FACISB) Universidade Estadual Paulista (UNESP) |
| Databáze: | OpenAIRE |
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